Brereton A, Russell W J
Department of Anaesthesia, Royal Adelaide Hospital, University of Adelaide, South Australia, Australia.
Anaesth Intensive Care. 2012 Sep;40(5):861-6. doi: 10.1177/0310057X1204000515.
We audited patients with anaphylaxis to muscle relaxants during anaesthesia referred to the Department of Anaesthesia at the Royal Adelaide Hospital between the start of 2000 and the end of 2009. Of the 220 patients tested during this period, 43 had a positive intradermal test to the muscle relaxant given during their anaesthetic. The majority of these were to rocuronium and suxamethonium. Where rocuronium was the index agent, 65% of patients cross-reacted with another relaxant and 29% of patients with suxamethonium as their index agent demonstrated cross-reaction with another relaxant.
我们对2000年初至2009年末转诊至皇家阿德莱德医院麻醉科、在麻醉期间发生对肌肉松弛剂过敏反应的患者进行了审计。在此期间接受检测的220例患者中，有43例对其麻醉期间使用的肌肉松弛剂皮内试验呈阳性。其中大多数是对罗库溴铵和琥珀胆碱。以罗库溴铵作为索引药物时，65%的患者与另一种松弛剂发生交叉反应；以琥珀胆碱作为索引药物的患者中，29%与另一种松弛剂发生交叉反应。
