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快速康复外科的未来展望与研究倡议

Future perspectives and research initiatives in fast-track surgery.

作者信息

Kehlet Henrik

机构信息

Section for Surgical Pathophysiology, the Juliane Marie Centre, 4074, Rigshospitalet, 2100 Copenhagen, Denmark.

出版信息

Langenbecks Arch Surg. 2006 Sep;391(5):495-8. doi: 10.1007/s00423-006-0087-8. Epub 2006 Aug 19.

Abstract

BACKGROUND AND AIMS

Major surgery is still followed by a risk of morbidity, a need for hospitalisation and convalescence. Fast-track surgery has been introduced as a coordinated effort to combine unimodal evidence-based principles of care into a multi-modal effort to enhance recovery. The aim of this article was to update recent data on fast-track abdominal surgery and outline future strategies for research.

RESULTS

The data from fast-track colonic resection support the validity of the concept because pain, ileus, cardiopulmonary function and muscle function were all improved, compared with traditional treatment and with reduced post-operative fatigue and convalescence. Although less data is available, similar positive results may be achieved in other types of major surgery. Current research initiatives include improved multi-modal non-opioid analgesia, rational principles for perioperative fluid management, pharmacological reduction of surgical stress responses and the role of laparoscopic procedures within the fast-track concept.

CONCLUSIONS

Fast-track surgery has evolved as a valid concept to improve post-operative outcome. Further progress may be expected based upon intensified research within perioperative pathophysiology and a multi-disciplinary collaboration between surgeons, anaesthesiologists and surgical nurses.

摘要

背景与目的

大手术后仍存在发病风险、需要住院及康复。快速康复外科已被引入,作为一种协调的努力,将基于循证医学的单模式护理原则整合为多模式努力以促进恢复。本文旨在更新关于快速康复腹部手术的最新数据,并概述未来的研究策略。

结果

快速康复结肠切除术的数据支持了这一概念的有效性,因为与传统治疗相比,疼痛、肠梗阻、心肺功能和肌肉功能均得到改善,且术后疲劳和康复时间缩短。虽然可用数据较少,但在其他类型的大手术中可能也会取得类似的积极结果。当前的研究举措包括改进多模式非阿片类镇痛、围手术期液体管理的合理原则、手术应激反应的药物减轻以及腹腔镜手术在快速康复概念中的作用。

结论

快速康复外科已发展成为一个改善术后结局的有效概念。基于围手术期病理生理学的深入研究以及外科医生、麻醉医生和外科护士之间的多学科合作,有望取得进一步进展。

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