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与硬脊膜内蛛网膜囊肿相关的脊髓空洞症。

Syringomyelia associated with intradural arachnoid cysts.

作者信息

Holly Langston T, Batzdorf Ulrich

机构信息

Division of Neurosurgery, David Geffen School of Medicine, University of California at Los Angeles, California 90095, USA.

出版信息

J Neurosurg Spine. 2006 Aug;5(2):111-6. doi: 10.3171/spi.2006.5.2.111.

Abstract

OBJECT

Intradural arachnoid cysts are relatively uncommon pouches of cerebrospinal fluid (CSF) found within the subarachnoid space. The authors present a series of eight symptomatic patients in whom syrinx cavities were associated with arachnoid cysts, and they discuss treatment strategies for this entity.

METHODS

The population comprised eight men whose mean age was 50 years (range 35-81 years). All patients experienced gait difficulty, and it was the chief complaint in seven; arm pain was the primary complaint in one. No patient had a history of spinal trauma, meningitis, or previous spinal surgery at the level of the syrinx cavity or arachnoid cyst. In each patient imaging revealed a syrinx cavity affecting two to 10 vertebral levels. Posterior thoracic arachnoid cysts were found in proximity to the syrinx cavity in each case. There was no evidence of cavity enhancement, Chiari malformation, tethered cord, or hydrocephalus. All patients underwent thoracic laminectomy and resection of the arachnoid cyst wall, and postoperative neurological improvement was documented in each case. The mean follow-up duration was 19 months (range 4-37 months). Follow-up magnetic resonance imaging demonstrated the disappearance of the arachnoid cyst and a significant decrease in syrinx cavity size in each patient.

CONCLUSIONS

Spinal arachnoid cysts can be associated with syringomyelia, likely due to alterations in normal CSF dynamics. In symptomatic patients these cysts should be resected and the normal CSF flow restored. The results of the present series indicate that neurological improvement and reduction in syrinx cavity size can be achieved in patients with syringomyelia associated with intradural arachnoid cysts.

摘要

目的

硬脊膜内蛛网膜囊肿是在蛛网膜下腔内发现的相对罕见的脑脊液(CSF)囊袋。作者报告了一系列8例有症状的患者,这些患者的脊髓空洞症与蛛网膜囊肿相关,并讨论了该疾病的治疗策略。

方法

研究对象为8名男性,平均年龄50岁(范围35 - 81岁)。所有患者均有步态困难,其中7例以此为主诉;1例以手臂疼痛为主诉。所有患者均无脊髓创伤、脑膜炎病史,在脊髓空洞症或蛛网膜囊肿水平处也无既往脊柱手术史。每位患者的影像学检查均显示脊髓空洞症累及2至10个椎体节段。每例患者在脊髓空洞症附近均发现后胸段蛛网膜囊肿。无空洞强化、Chiari畸形、脊髓拴系或脑积水的证据。所有患者均接受了胸椎椎板切除术及蛛网膜囊肿壁切除术,且每例患者术后神经功能均有改善。平均随访时间为19个月(范围4 - 37个月)。随访磁共振成像显示每位患者的蛛网膜囊肿消失,脊髓空洞症大小显著减小。

结论

脊髓蛛网膜囊肿可能与脊髓空洞症相关,可能是由于正常脑脊液动力学改变所致。对于有症状的患者,应切除这些囊肿并恢复正常脑脊液流动。本系列研究结果表明,对于与硬脊膜内蛛网膜囊肿相关的脊髓空洞症患者,可实现神经功能改善及脊髓空洞症大小减小。

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