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转移性肝肿瘤的外科治疗。

Surgical treatment of metastatic liver tumors.

作者信息

Foster J H

机构信息

University of Connecticut School of Medicine, Farmington.

出版信息

Hepatogastroenterology. 1990 Apr;37(2):182-7.

PMID:1692803
Abstract

Liver resection for limited amounts of metastatic cancer should be recommended to highly selected patients. It will provide a significant chance for "cure" for patients with metastases from colorectal cancers and may provide palliation for a few others with very slow-growing tumors or hormone symptoms from endocrine tumors. The results of resection are compared with those of chemotherapy, radiation, arterial ligation, and other treatments. Selection criteria, none of which is absolute, include number of metastases, stage of primary tumor, interval between resection of primary tumor and discovery of liver metastasis, and proximity to vital structures. The presence of extrahepatic metastasis, even if resected, carries with it a grim prognosis and should probably preclude liver resection.

摘要

对于少量转移性癌症患者,应向经过严格筛选的患者推荐肝切除术。这将为患有结直肠癌转移的患者提供显著的“治愈”机会,对于少数其他肿瘤生长缓慢或患有内分泌肿瘤激素症状的患者,也可能提供缓解。将肝切除的结果与化疗、放疗、动脉结扎及其他治疗方法的结果进行比较。选择标准(没有一个是绝对的)包括转移灶数量、原发肿瘤分期、原发肿瘤切除与肝转移发现之间的间隔时间以及与重要结构的接近程度。存在肝外转移,即使已切除,预后也很严峻,可能应排除肝切除术。

相似文献

1
Surgical treatment of metastatic liver tumors.转移性肝肿瘤的外科治疗。
Hepatogastroenterology. 1990 Apr;37(2):182-7.
2
Treatment for extrahepatic metastasis of hepatocellular carcinoma following successful hepatic resection.肝切除成功后肝细胞癌肝外转移的治疗
Hepatogastroenterology. 1999 Sep-Oct;46(29):2931-4.
3
[Diagnosis and treatment of colorectal liver metastases - workflow].[结直肠癌肝转移的诊断与治疗——工作流程]
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Characteristic differences between patients who have undergone surgical treatment for lung metastasis or hepatic metastasis from colorectal cancer.接受过结直肠癌肺转移或肝转移手术治疗的患者之间的特征差异。
Thorac Cardiovasc Surg. 2005 Dec;53(6):358-64. doi: 10.1055/s-2005-865758.
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[Liver surgery: what is feasible?].[肝脏手术:哪些是可行的?]
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P53 mutations in primary tumors and subsequent liver metastases are related to survival in patients with colorectal carcinoma who undergo liver resection.原发性肿瘤和随后发生的肝转移中的P53突变与接受肝切除的结直肠癌患者的生存情况相关。
Cancer. 2001 Feb 15;91(4):727-36.
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[Liver resection. I].[肝脏切除术。I]
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[Studies on the effectiveness of adjuvant hepatic arterial chemotherapy after hepatectomy for primary or metastatic liver cancer].[肝切除术后辅助肝动脉化疗对原发性或转移性肝癌的疗效研究]
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[Metastatic disease of the liver: surgical perspective].
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Therapeutic results for hepatic metastasis of colorectal cancer with special reference to effectiveness of hepatectomy: analysis of prognostic factors for 763 cases recorded at 18 institutions.结直肠癌肝转移的治疗结果:特别提及肝切除术的有效性——对18家机构记录的763例病例的预后因素分析
Dis Colon Rectum. 2003 Oct;46(10 Suppl):S22-31. doi: 10.1097/01.DCR.0000089106.71914.00.

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Radiat Oncol. 2015 Mar 20;10:69. doi: 10.1186/s13014-015-0369-9.