Foster J H
University of Connecticut School of Medicine, Farmington.
Hepatogastroenterology. 1990 Apr;37(2):182-7.
Liver resection for limited amounts of metastatic cancer should be recommended to highly selected patients. It will provide a significant chance for "cure" for patients with metastases from colorectal cancers and may provide palliation for a few others with very slow-growing tumors or hormone symptoms from endocrine tumors. The results of resection are compared with those of chemotherapy, radiation, arterial ligation, and other treatments. Selection criteria, none of which is absolute, include number of metastases, stage of primary tumor, interval between resection of primary tumor and discovery of liver metastasis, and proximity to vital structures. The presence of extrahepatic metastasis, even if resected, carries with it a grim prognosis and should probably preclude liver resection.
对于少量转移性癌症患者,应向经过严格筛选的患者推荐肝切除术。这将为患有结直肠癌转移的患者提供显著的“治愈”机会,对于少数其他肿瘤生长缓慢或患有内分泌肿瘤激素症状的患者,也可能提供缓解。将肝切除的结果与化疗、放疗、动脉结扎及其他治疗方法的结果进行比较。选择标准(没有一个是绝对的)包括转移灶数量、原发肿瘤分期、原发肿瘤切除与肝转移发现之间的间隔时间以及与重要结构的接近程度。存在肝外转移,即使已切除,预后也很严峻,可能应排除肝切除术。