Penafiel Alvin, Lee Pyng, Hsu Anne, Eng Philip
Department of Respiratory and Critical Care Medicine, Singapore General Hospital, Singapore.
Ann Thorac Surg. 2006 Sep;82(3):e22-3. doi: 10.1016/j.athoracsur.2006.05.067.
An elderly woman with post-tuberculous stricture of the lower trachea and main bronchi underwent laser re-canalization, balloon dilation, and silicone stent insertion in the lower trachea and main bronchi. Subsequently she had recurrent dyspnea develop due to obstructing granulomas, which necessitated four endoscopic procedures in 2 years. The tracheal stent was removed and topical mitomycin-C was applied using saturated pledgets at a dose of 0.5 mg/mL for 2 minutes each over the lower trachea and both orifices of the main bronchi. Follow-up for 24 months showed no recurrence of symptoms. Bronchoscopy and spirometry performed at 2, 6, and 12 months showed resolution of the granulomas.
一名患有气管下段及主支气管结核后狭窄的老年女性接受了激光再通、球囊扩张以及气管下段和主支气管硅酮支架置入术。随后，她因阻塞性肉芽肿出现反复呼吸困难，在2年内需要进行4次内镜检查。取出气管支架，使用饱和棉球以0.5 mg/mL的剂量在下段气管及主支气管的两个开口处局部应用丝裂霉素-C，每次2分钟。24个月的随访显示症状未复发。在2个月、6个月和12个月时进行的支气管镜检查和肺功能测定显示肉芽肿消退。
