Gilbert Sunny D, Batey Robert T
Department of Chemistry and Biochemistry, University of Colorado-Boulder, Campus Box 215, Boulder, CO 80309, USA.
Chem Biol. 2006 Aug;13(8):805-7. doi: 10.1016/j.chembiol.2006.08.002.
Riboswitches in the 5'-untranslated regions of mRNAs cotranscriptionally couple ligand binding and gene regulation. In this issue of Chemistry & Biology, Lemay et al. describe folding of a key tertiary interaction in the adenine riboswitch and its mechanistic consequences.
mRNA 5'非翻译区中的核糖开关在转录过程中耦合配体结合与基因调控。在本期《化学生物学》中，勒梅等人描述了腺嘌呤核糖开关中一种关键三级相互作用的折叠及其机制后果。
