Crusats Joaquim, Veintemillas-Verdaguer Sabino, Ribó Josep M
Departament de Química Orgànica Universitat de Barcelona, c. Martí i Franquès 1.08028 Barcelona, Catalonia, Spain.
Chemistry. 2006 Oct 16;12(30):7776-81. doi: 10.1002/chem.200600580.
Recent results on the crystallisation/dissolution equilibrium of enantiomorphic crystals of NaClO3 lead to the conclusion that liquid-phase systems composed of achiral or fast racemising compounds yielding enantiomorphic solid phases (racemic conglomerates) can derive spontaneously to a single homochiral solid phase. This is a thermodynamically driven total resolution, which can only occur when the system is so perturbed that chiral recognition between the species of the system becomes feasible.
近期关于氯酸钠对映体晶体结晶/溶解平衡的研究结果表明，由非手性或快速外消旋化合物组成的液相体系，若能产生对映体固相（外消旋聚集体），则可自发地转变为单一的纯手性固相。这是一种由热力学驱动的完全拆分，只有当体系受到足够扰动，使得体系中各物种之间的手性识别变得可行时才会发生。
