Arienzo D, Babiloni C, Ferretti A, Caulo M, Del Gratta C, Tartaro A, Rossini P M, Romani G L
Department of Clinical Sciences and Bioimaging, G. D'Annunzio University, Chieti, Italy.
Neuroimage. 2006 Nov 1;33(2):700-5. doi: 10.1016/j.neuroimage.2006.06.030. Epub 2006 Aug 28.
In this study, we tested whether there is a somatotopic sensory organization in human anterior cingulate cortex (ACC) and supplementary motor area (SMA), as a reflection of central feed-back sensory processing for motor control. To this aim, fMRI recordings were performed in 15 normal young adults during nonpainful and painful electric stimulation of median nerve at the wrist and tibial nerve at the medial malleolus. Results showed that the representation of median nerve area was more anterior in the ACC and more inferior in the SMA than the one of tibial nerve area. This was true for both nonpainful and painful stimulation intensities. These results point to a somatotopic sensory organization of human ACC and SMA.
在本研究中，我们测试了人类前扣带回皮质（ACC）和辅助运动区（SMA）是否存在躯体感觉定位组织，以此作为运动控制中枢反馈感觉处理的一种反映。为此，我们对15名正常年轻成年人在腕部正中神经和内踝胫神经进行无痛和疼痛性电刺激期间进行了功能磁共振成像（fMRI）记录。结果显示，与胫神经区域相比，正中神经区域在ACC中的代表区更靠前，在SMA中的代表区更低。无论是无痛还是疼痛刺激强度，都是如此。这些结果表明人类ACC和SMA存在躯体感觉定位组织。
