Roy K K, Baruah Jinee, Kumar Sunesh, Malhotra Neena, Deorari A K, Sharma J B
Department of Pediatrics, All India Institute of Medical Science, New Delhi, India.
Indian J Pediatr. 2006 Aug;73(8):669-73. doi: 10.1007/BF02898441.
To evaluate the antenatal profile of the mother and the immediate neonatal morbidity and mortality till discharge.
The study was a retrospective analysis of 92 patients of preterm labour who delivered babies weighing
A total of 92 mothers in preterm labour at 26 to 34 weeks were admitted and subsequently delivered 70 VLBW babies (< 1500 gms) and 36 ELBW babies (< 1000 gms) including 8 pairs of twins and 3 triplets pregnancies. Majority of the patients (93.4%) were booked. Amongst the various high risk factors for preterm labour, anaemia during pregnancy (32.6%), bacterial vaginosis (26%), gestational hypertension (18.4%) and pervious history of preterm labour (18.4%) were common associations. Calcium channel blocker (Depin) tocolysis was effective in postponing labour from 48 hours to more than 2 weeks. The cesarean section rate was very high (67.3%) in our study. The commoner neonatal complications in both VLBW and ELBW babies were RDS, neonatal jaundice and sepsis. Features of IUGR were seen in both the groups (22.8% in VLBW and 22.2% in ELBW babies). The neonatal mortality rate till discharge was 15.7% in VLBW group and 33.3% in ELBW group. The morality rate was highest in 26 to 30 weeks gestation babies and in babies weighing < 800 gms.
Antenatal profile of preterm labour in our series showed a number of high risk factors. The identification of common high risk factors is important for appropriate prenatal care. A better neonatal survival rate was possible due to timely intervention, appropriate management and NICU care facility available in our tertiary care centre.
评估母亲的产前情况以及直至出院时新生儿的即刻发病率和死亡率。
本研究对92例早产患者进行回顾性分析，这些患者所分娩婴儿的体重……
共有92例孕26至34周的早产母亲入院，随后分娩了70例极低出生体重儿（<1500克）和36例超低出生体重儿（<1000克），包括8对双胞胎和3例三胞胎妊娠。大多数患者（93.4%）已登记建档。在早产的各种高危因素中，孕期贫血（32.6%）、细菌性阴道病（26%）、妊娠期高血压（18.4%）和既往早产史（18.4%）是常见的关联因素。钙通道阻滞剂（地尔硫䓬）抑制宫缩在将分娩推迟48小时至超过2周方面有效。在我们的研究中剖宫产率非常高（67.3%）。极低出生体重儿和超低出生体重儿中较常见的新生儿并发症是呼吸窘迫综合征、新生儿黄疸和败血症。两组均可见胎儿生长受限特征（极低出生体重儿中为22.8%，超低出生体重儿中为22.2%）。直至出院时，极低出生体重儿组的新生儿死亡率为15.7%，超低出生体重儿组为33.3%。死亡率在孕26至30周的婴儿以及体重<800克的婴儿中最高。
我们系列研究中早产的产前情况显示出一些高危因素。识别常见的高危因素对于适当的产前护理很重要。由于我们三级护理中心能够及时干预、进行适当管理并提供新生儿重症监护病房设施，提高新生儿存活率是可能的。
