Viola Chiara, Asselah Tarik, Samuel Didier, Durand François, Boudjema Hamza, Valla Dominique, Marcellin Patrick
Service d'Hépatologie, INSERM CRB3, University of Paris VII, Hôpital, Beaujon, Clichy 92 110, France.
World J Gastroenterol. 2006 Aug 14;12(30):4911-3. doi: 10.3748/wjg.v12.i30.4911.
We described a 59-year-old male patient who underwent liver transplantation in 1989 for hepatocellular carcinoma (HCC) complicating hepatitis B virus (HBV) cirrhosis. In 2001 (12 years after liver transplantation), he developed a lung metastasis of HCC without intrahepatic recurrence and the resection was done. In July 2003, he was symptom free without any recurrence. HCC metastasis can develop even after a very long time of liver transplantation. Many HCCs grow slowly, and the growth rate of recurrent tumors in patients receiving immunosuppressive therapy is significantly greater than that of those who do not receive immunosuppressive therapy.
我们描述了一位59岁的男性患者,他于1989年因乙型肝炎病毒(HBV)肝硬化合并肝细胞癌(HCC)接受了肝移植。2001年(肝移植后12年),他出现了HCC肺转移,无肝内复发,并接受了切除术。2003年7月,他无症状且无任何复发。即使在肝移植很长时间后,HCC转移仍可能发生。许多HCC生长缓慢,接受免疫抑制治疗患者的复发肿瘤生长速度明显快于未接受免疫抑制治疗的患者。