大鼠主嗅球和副嗅球中的肽能颗粒细胞群体。

Peptidergic granule cell populations in the rat main and accessory olfactory bulb.

作者信息

Gouda M, Matsutani S, Senba E, Tohyama M

机构信息

Department of Anatomy (II), Osaka University Medical School, Japan.

出版信息

Brain Res. 1990 Apr 2;512(2):339-42. doi: 10.1016/0006-8993(90)90645-R.

DOI:10.1016/0006-8993(90)90645-R

PMID:1693871

Abstract

The distribution and incidence of substance P (SP)- and Met-enkephalin-Arg6-Gly7-Leu8 (ENK-8)-like immunoreactive granule cells in the main and accessory olfactory bulbs of male rats was studied immunohistochemically. In the granule cell layer of the main olfactory bulb, numerous ENK-8-like immunoreactive granule cells were observed but SP-like immunoreactive ones were rare (less than 1%). On the other hand, in the granule cell layer of the accessory olfactory bulb, both SP-like immunoreactive and ENK-8-like immunoreactive granule cells were numerous. 15-20% of these neurons contained both the peptides.

摘要

采用免疫组织化学方法研究了雄性大鼠主嗅球和副嗅球中P物质（SP）和甲硫氨酸脑啡肽-精氨酸6-甘氨酸7-亮氨酸8（ENK-8）样免疫反应性颗粒细胞的分布和发生率。在主嗅球的颗粒细胞层中，观察到大量ENK-8样免疫反应性颗粒细胞，但SP样免疫反应性颗粒细胞很少（少于1%）。另一方面，在副嗅球的颗粒细胞层中，SP样和ENK-8样免疫反应性颗粒细胞都很多。这些神经元中有15%-20%同时含有这两种肽。