Wu Zhen-Fang, Liu De-Wu, Wang Qing-Lai, Zeng Hai-Yu, Chen Yao-Shen, Zhang Hao
College ofAnimal Science, South China Agricultural University, Guangzhou.
Yi Chuan Xue Bao. 2006 Aug;33(8):711-6. doi: 10.1016/S0379-4172(06)60103-0.
To study the potential use of estrogen receptor gene (ESR) as a genetic marker to improve the reproductive traits of pigs, the genotypes of the ESR PCR product digested by Pvu II were determined in 2,239 litters from 612 Landrace sows. The data of the first, second, and later parities were separately evaluated. Although the frequency of the B allele was much lower than that of the A allele, likelihood ratio test showed that the gene frequencies were in Hardy-Weinberg equilibrium. The effects of ESR of different parities were not equal. In summary, the sows with the BB genotype showed better performance for total number of piglets born (TNB) and number of piglets born alive (NBA), but had a lower average piglet weight at birth (AWB). It was concluded that ESR could be used as a marker for the selection of litter size in the Landrace population.
为研究雌激素受体基因（ESR）作为一种遗传标记用于改善猪繁殖性状的潜在用途，对612头长白母猪的2239窝仔猪进行了Pvu II酶切的ESR PCR产物基因型测定。分别评估了头胎、二胎及以后胎次的数据。尽管B等位基因的频率远低于A等位基因，但似然比检验表明基因频率处于哈迪-温伯格平衡。不同胎次的ESR效应不相等。总之，BB基因型母猪的总产仔数（TNB）和产活仔数（NBA）表现较好，但出生时仔猪平均体重（AWB）较低。得出结论，ESR可作为长白猪群体产仔数选择的一个标记。
