Kreher Nerissa C, Pescovitz Ora Hirsch, Delameter Paul, Tiulpakov Anatoly, Hochberg Ze'ev
Department of Pediatrics, Section of Pediatric Endocrinology and Diabetology, Riley Hospital for Children, Indiana University School of Medicine, Indianapolis, IN, USA.
J Pediatr. 2006 Sep;149(3):416-20. doi: 10.1016/j.jpeds.2006.04.027.
This report describes the use of bicalutamide and anastrozole in two subjects with familial male-limited precocious puberty. Clinical improvements include decreased facial acne and pubic hair. Most importantly, a marked decrease in growth velocity and skeletal advancement has been achieved.
本报告描述了比卡鲁胺和阿那曲唑在两名家族性男性限性早熟患者中的应用。临床改善包括面部痤疮和阴毛减少。最重要的是,生长速度和骨骼发育显著降低。