在一名促黄体生成素受体存在新突变的男孩中，使用阿那曲唑和比卡鲁胺治疗家族性男性限局性性早熟（睾丸中毒症）
Treatment of familial male-limited precocious puberty (testotoxicosis) with anastrozole and bicalutamide in a boy with a novel mutation in the luteinizing hormone receptor.
作者信息
Mitre Naim, Lteif Aida
机构信息
Division of Pediatric Endocrinology and Metabolism, Mayo Clinic College of Medicine, Rochester, MN 55905, USA.
出版信息
J Pediatr Endocrinol Metab. 2009 Dec;22(12):1163-7. doi: 10.1515/jpem.2009.22.12.1163.
PMID:20333877
Abstract
We report the use of anastrozole and bicalutamide in a 5 year-old boy with familial male-limited precocious puberty. Clinical response showed decreased advancement of skeletal maturation, secondary sexual characteristics and aggressiveness with no short-term side effects. The combination seems a better option until long-term data are available.
摘要
我们报告了一名5岁患有家族性男性限性性早熟男孩使用阿那曲唑和比卡鲁胺的情况。临床反应显示骨骼成熟进程减缓、第二性征及攻击性降低，且无短期副作用。在获得长期数据之前，联合用药似乎是更好的选择。
Zotero 插件