Gascard-Battisti C, Dubois-Lebbe C, Chatelet-Cheront C, Ferrant L, Sales A, Houzé de l'Aulnoit D
Maternité Saint-Vincent-de-Paul, Faculté Libre de Médecine de Lille, Boulevard de Belfort, BP 387, 59020 Lille Cedex.
J Gynecol Obstet Biol Reprod (Paris). 2006 Sep;35(5 Pt 1):472-6. doi: 10.1016/s0368-2315(06)76419-5.
Congenital heart disease is often severe and outcome remains uncertain. In some cases, early intervention at birth can improve the prognosis. Prenatal detection of congenital heart disease by ultrasound may improve outcome for foetuses with congenital heart disease but today, results are not convincing. The purpose of this review was to describe the detection of congenital heart disease in a non selected population.
A retrospective study was undertaken to evaluate the prenatal detection of congenital heart disease in our department from 1984 to 2003.
Incidence of congenital heart disease was 4.9. Sensitivity of detection was 60%, specificity was 99.9%. Most cases were severe heart diseases. In 57 fetuses (40%), congenital heart disease was not detected. Thirty-seven fetuses (65%) presented minor disease; in 20 fetuses (35%), congenital heart disease was found to be severe. Effectiveness of detection of major congenital heart diseases has increased since 2000.
Large-scale fetal heart screening is necessary for early detection of congenital heart disease and improved outcome.
先天性心脏病通常病情严重，预后仍不确定。在某些情况下，出生时的早期干预可改善预后。通过超声进行先天性心脏病的产前检测可能会改善患有先天性心脏病胎儿的预后，但目前，结果并不令人信服。本综述的目的是描述在未经过筛选的人群中先天性心脏病的检测情况。
进行了一项回顾性研究，以评估1984年至2003年我们科室先天性心脏病的产前检测情况。
先天性心脏病的发病率为4.9。检测的敏感性为60%，特异性为99.9%。大多数病例为严重心脏病。在57例胎儿（40%）中，未检测出先天性心脏病。37例胎儿（65%）患有轻度疾病；20例胎儿（35%）被发现患有严重的先天性心脏病。自2000年以来，主要先天性心脏病的检测有效性有所提高。
大规模胎儿心脏筛查对于早期发现先天性心脏病和改善预后是必要的。
