铅中毒所致膝关节骨坏死：病例报告及文献复习
Knee osteonecrosis due to lead poisoning: case report and review of the literature.
作者信息
Kazakos Konstantinos, Chatzipapas Christos, Xarchas Konstantinos C, Mantatzis Michael, Tilkeridis Konstantinos, Galanis Vasilios, Verettas Dionisios A
机构信息
Department of Orthopaedics, Democritus University of Thrace Medical School, Alexandroupolis, Greece.
出版信息
Med Sci Monit. 2006 Sep;12(9):CS85-9.
BACKGROUND
Though rare, a relationship between toxic heavy-metal accumulation and bone necrosis exists.
CASE REPORT
A 28-year-old man suffered from chronic bilateral knee pain accompanied by muscle fibrillations and night cramps. On examiniation he presented tenderness and mild quadriceps muscle atrophy, but unaffected range of movement, sensation, and tendon reflexes and no effuision. He also complained of blurred vision, lethargy, and tremor.
CONCLUSIONS
On the basis of these data it appeared that these infarcts were attributable to lead poisoning. This situation has not been described in the knee region, but finrther clarification of a possible causal relationship between toxic trace element concentration and idiopathic bone necrosis appears necessary.
背景
尽管罕见，但有毒重金属积累与骨坏死之间存在关联。
病例报告
一名28岁男性患有双侧膝关节慢性疼痛，伴有肌肉纤维震颤和夜间抽筋。检查时，他表现出压痛和股四头肌轻度萎缩，但活动范围、感觉、肌腱反射未受影响，且无积液。他还主诉视力模糊、嗜睡和震颤。
结论
根据这些数据，这些梗死似乎归因于铅中毒。这种情况在膝关节区域尚未有过描述，但进一步阐明有毒微量元素浓度与特发性骨坏死之间可能的因果关系似乎很有必要。
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