Arkin Adam P, Fletcher Daniel A
Howard Hughes Medical Institute, Department of Bioengineering, University of California, Berkeley, CA 94720, USA.
Genome Biol. 2006;7(8):114. doi: 10.1186/gb-2006-7-8-114.
Efforts to manipulate living organisms have raised the question of whether engineering principles of hierarchy, abstraction and design can be applied to biological systems. Here, we consider the practical challenges to controlling living organisms that must be surmounted, or at least managed, if synthetic biology and cellular bioengineering are to be productive.
操纵生物体的努力引发了一个问题,即层次结构、抽象和设计等工程原理是否可以应用于生物系统。在这里,我们考虑如果合成生物学和细胞生物工程要取得成效,控制生物体必须克服或至少应对的实际挑战。