Sambol Elliot, Patterson Danielle, Rivera Rafael, Borys Dariusz, Greco M Alba, Kaul Aditya, Nadler Evan P
Division of Pediatric Surgery, Department of Surgery, New York University School of Medicine, 530 First Avenue, Suite 10 W, New York, NY 10016, USA.
Pediatr Surg Int. 2006 Oct;22(10):865-8. doi: 10.1007/s00383-006-1773-x. Epub 2006 Aug 30.
Children with acquired immunodeficiency syndrome (AIDS) are at an increased risk for lymphoproliferative and neoplastic disorders. Included among these are smooth muscle neoplasms such as leiomyomas and leiomyosarcomas. There have been at least 15 reported cases of smooth muscle tumors in the approximately 8,000 children with AIDS, however the incidence in immunocompetent children is only two per ten million. The lesions in children with human immunodeficiency virus infection are usually found in the lung, liver, and gastrointestinal tract. Here, we present an unusual case of a 12-year-old African American girl with vertically acquired AIDS who presented to the pediatric emergency department with severe diffuse abdominal pain. She was ultimately found to have an appendiceal leiomyoma on abdominal exploration, the first reported case. Our report suggests that smooth muscle tumors of the appendix be included in the differential diagnosis of abdominal masses in children with AIDS.
患有获得性免疫缺陷综合征（艾滋病）的儿童患淋巴增生性疾病和肿瘤性疾病的风险增加。其中包括平滑肌瘤和平滑肌肉瘤等平滑肌肿瘤。在约8000名患艾滋病的儿童中，至少有15例报告的平滑肌肿瘤病例，然而免疫功能正常的儿童中的发病率仅为千万分之二。感染人类免疫缺陷病毒的儿童的病变通常见于肺、肝和胃肠道。在此，我们报告一例不寻常的病例，一名12岁的非裔美国女孩，垂直感染艾滋病，因严重弥漫性腹痛就诊于儿科急诊科。经腹部探查，最终发现她患有阑尾平滑肌瘤，这是首例报告病例。我们的报告表明，艾滋病儿童腹部肿块的鉴别诊断应包括阑尾平滑肌瘤。
