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[钴缺乏大鼠的碘、碳水化合物及蛋白质代谢]

[Iodine, carbohydrate and protein metabolism in rats with cobalt deficiency].

作者信息

Marsakova N V, Esipenko B E

出版信息

Fiziol Zh (1978). 1990 Mar-Apr;36(2):43-50.

PMID:1694504
Abstract

Experiments on male rats maintained at the diet with a low amount of cobalt have revealed a decrease in values of iodine indices in organs and tissues except for the liver tissues where a sharp increase in the inorganic iodine concentration as well as disturbances of the protein and carbohydrate metabolism were observed. Mathematical analysis has shown a high correlation of changes in the carbohydrate and protein metabolism and concentration of protein-bound iodine in blood. It has permitted a conclusion on an indirect effect of the cobalt deficiency on the metabolism processes as a result of changes in the concentration of protein-bound iodine in blood and tissues.

摘要

对食用低钴含量饮食的雄性大鼠进行的实验表明,除肝脏组织外,器官和组织中的碘指数值有所下降。在肝脏组织中,观察到无机碘浓度急剧增加以及蛋白质和碳水化合物代谢紊乱。数学分析表明,碳水化合物和蛋白质代谢的变化与血液中蛋白质结合碘的浓度高度相关。由此可以得出结论,由于血液和组织中蛋白质结合碘浓度的变化,钴缺乏对代谢过程产生间接影响。

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