使用TA荧光对高强度聚焦超声（HIFU）暴露引起的空化活动峰值进行的研究。
Study of a peak in cavitation activity from HIFU exposures using TA fluorescence.
作者信息
Zhu Changping, He Shichuan, Shan Minglei, Chen Jiacai
机构信息
State Key Laboratory of Hydrology-water Resources and Hydraulic Engineering, Department of Computer and Information Engineering, Hohai University, ChangZhou, PR China.
出版信息
Ultrasonics. 2006 Dec 22;44 Suppl 1:e349-51. doi: 10.1016/j.ultras.2006.07.016. Epub 2006 Aug 11.
Methods of measuring the sound field and focal region of a 1.05 MHz high intensity focused ultrasound (HIFU) are described in this paper. 1.05 MHz pulsed HIFU with intensity 2400 W/cm(2) with a 1:1 duty cycle ("on" phase equaled "off" phase) was used to irradiate terephthalic acid (TA). Pulse periods of 0.5 ms, 1 ms, 3.3 ms, 10 ms, 15 ms, 33 ms, 0.1s and 1s were used. The irradiation time was 2 min. To indicate the intensity of inertial cavitation activity, the fluorescence intensity of hydroxyterephthalic acid (HTA) was measured. The result shows that the cavitation activity of pulsed HIFU peaks at a pulse period of 10 ms, cavitation activity is significantly greater for pulse periods from 2 to 20 ms than for others.
本文描述了测量1.05兆赫兹高强度聚焦超声（HIFU）声场和焦点区域的方法。使用强度为2400瓦/平方厘米、占空比为1:1（“开”相位等于“关”相位）的1.05兆赫兹脉冲HIFU照射对苯二甲酸（TA）。使用了0.5毫秒、1毫秒、3.3毫秒、10毫秒、15毫秒、33毫秒、0.1秒和1秒的脉冲周期。照射时间为2分钟。为了指示惯性空化活动的强度，测量了羟基对苯二甲酸（HTA）的荧光强度。结果表明，脉冲HIFU的空化活动在脉冲周期为10毫秒时达到峰值，在2至20毫秒的脉冲周期内，空化活动明显大于其他周期。
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