Bower W F, Sit F K Y, Yeung C K
Division of Paediatric Surgery and Paediatric Urology, Department of Surgery, Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, New Territories, Hong Kong.
J Urol. 2006 Oct;176(4 Pt 2):1771-5. doi: 10.1016/j.juro.2006.04.087.
Since nocturnal enuresis in adults and adolescents is rarely monosymptomatic, we identified the prevalence of childhood bladder and bowel dysfunction, and compared findings to those in a normative cohort.
Childhood and current bladder and bowel dysfunction were investigated in 56 consecutive adolescents and adults attending a public nocturnal enuresis service and in 293 normative adults using a self-administered questionnaire. Analysis involved descriptive statistics, the chi-square and Kruskal-Wallis tests, and regression analysis with p <0.05 considered significant.
Adolescents and adults attending a public nocturnal enuresis service had significantly higher childhood scores than normative adults, and significantly more childhood urgency, frequency, urge incontinence, infrequent voiding and small volume, high urge voids. Infrequent bowel action and fecal soiling in childhood were also significantly more common in those with nocturnal enuresis than in controls. Adult symptoms of urge incontinence, general bowel symptoms and nocturnal enuresis were significantly more common in adults and adolescents with nocturnal enuresis. Significant associations were found between childhood symptoms and adult overactive bladder, and childhood emptying dysfunction and adult voiding dysfunction. Higher childhood scores in adults and adolescents with nocturnal enuresis correlated significantly with current adult symptoms of urge, urge leakage, stress incontinence, hesitancy, incomplete emptying and UTI within the last year.
Significant childhood bladder and bowel symptoms along with more adult urge and bowel dysfunction were found in adults and adolescents with nocturnal enuresis. The association with adult urgency and urinary tract infection supports the likelihood of underlying bladder and or voiding dysfunction in unremitting nocturnal enuresis.
由于成人和青少年夜间遗尿很少是单一症状，我们确定了儿童膀胱和肠道功能障碍的患病率，并将结果与正常队列进行比较。
使用自行填写的问卷，对56名连续就诊于公共夜间遗尿服务机构的青少年和成人以及293名正常成人进行儿童期及当前膀胱和肠道功能障碍调查。分析包括描述性统计、卡方检验和Kruskal-Wallis检验，以及p<0.05为有统计学意义的回归分析。
就诊于公共夜间遗尿服务机构的青少年和成人的儿童期得分显著高于正常成人，且儿童期尿急、尿频、急迫性尿失禁、排尿次数少和尿量少、高急迫性排尿的情况显著更多。夜间遗尿患者儿童期排便不频繁和大便失禁也比对照组更常见。急迫性尿失禁、一般肠道症状和夜间遗尿的成人症状在患有夜间遗尿的成人和青少年中显著更常见。发现儿童期症状与成人膀胱过度活动症之间以及儿童期排空功能障碍与成人排尿功能障碍之间存在显著关联。患有夜间遗尿的成人和青少年儿童期得分较高与当前成人的尿急、急迫性漏尿、压力性尿失禁、排尿犹豫、排空不全以及过去一年内的尿路感染症状显著相关。
在患有夜间遗尿的成人和青少年中发现了显著的儿童期膀胱和肠道症状以及更多的成人急迫性和肠道功能障碍。与成人尿急和尿路感染的关联支持了持续性夜间遗尿存在潜在膀胱和/或排尿功能障碍的可能性。
