Kerber Kevin A, Brown Devin L, Lisabeth Lynda D, Smith Melinda A, Morgenstern Lewis B
Stroke Program, University of Michigan Health System, Ann Arbor, MI 48109-0316, USA.
Stroke. 2006 Oct;37(10):2484-7. doi: 10.1161/01.STR.0000240329.48263.0d. Epub 2006 Aug 31.
Dizziness, vertigo, and imbalance are common presenting symptoms in the emergency department. Stroke is a leading concern even when these symptoms occur in isolation. The objective of the present study was to determine the "real-world" proportion of stroke among patients presenting to the emergency department with these dizziness symptoms (DS).
From a population-based study, patients >44 years of age presenting with DS to the emergency department, or directly admitted to the hospital, were identified. Demographics, the frequency of new cerebrovascular events, and the frequency of isolated DS (ie DS with no other stroke screening term or accompanying neurologic signs or symptoms) were assessed. Multivariable logistic regression was used to evaluate the association of age, gender, ethnicity, and isolated DS with stroke/transient ischemic attack (TIA). The association of the presenting symptoms with stroke/TIA was also assessed.
Stroke/TIA was diagnosed in 3.2% (53 of 1666) of all patients with DS. Only 0.7% (9 of 1297) of those with isolated DS had a stroke/TIA. Patients with stroke/TIA were slightly older than those without stroke/TIA (69.3+/-11.7 vs 65.3+/-12.9, P=0.02). Male gender was associated with stroke/TIA, whereas isolated DS was negatively associated with stroke/TIA. Patients with imbalance (dizziness as referent) were more likely to have stroke/TIA.
The proportion of cerebrovascular events in patients presenting with dizziness, vertigo, or imbalance is very low. Isolated dizziness, vertigo, or imbalance strongly predicts a noncerebrovascular cause. The symptom of imbalance is a predictor of stroke/TIA.
头晕、眩晕和失衡是急诊科常见的就诊症状。即使这些症状单独出现,卒中也是主要的关注问题。本研究的目的是确定在急诊科出现这些头晕症状(DS)的患者中卒中的“实际”比例。
从一项基于人群的研究中,识别出年龄大于44岁、因DS到急诊科就诊或直接入院的患者。评估人口统计学特征、新发脑血管事件的频率以及孤立性DS(即无其他卒中筛查术语或伴随神经体征或症状的DS)的频率。使用多变量逻辑回归评估年龄、性别、种族和孤立性DS与卒中/短暂性脑缺血发作(TIA)的关联。还评估了就诊症状与卒中/TIA的关联。
所有DS患者中,3.2%(1666例中的53例)被诊断为卒中/TIA。孤立性DS患者中只有0.7%(1297例中的9例)发生了卒中/TIA。发生卒中/TIA的患者比未发生卒中/TIA的患者年龄稍大(69.3±11.7岁对65.3±12.9岁,P = 0.02)。男性与卒中/TIA相关,而孤立性DS与卒中/TIA呈负相关。有失衡症状的患者(以头晕为对照)更有可能发生卒中/TIA。
出现头晕、眩晕或失衡的患者中脑血管事件的比例非常低。孤立的头晕、眩晕或失衡强烈预示着非脑血管病因。失衡症状是卒中/TIA的一个预测因素。