Heimstad Runa, Romundstad Pål R, Eik-Nes Sturla H, Salvesen Kjell A
Department of Obstetrics and Gynecology and National Center for Fetal Medicine, St. Olavs Hospital, University Hospital, Trondheim, Norway.
Obstet Gynecol. 2006 Sep;108(3 Pt 1):500-8. doi: 10.1097/01.AOG.0000227783.65800.0f.
The aim of the study was to evaluate pregnancy outcomes by weeks of gestation. A second aim was to assess the outcomes in groups with spontaneous or induced labor.
This was a prospective cohort study of singleton pregnancies delivered after 37 weeks of pregnancy covering a well defined region in Norway from 1990 to 2001 (N = 27,514). Linear regression, chi 2 tests, and multivariable logistic regression analysis were used.
Maternal complications varied with gestational age, and were lowest at 39 weeks and highest postterm (cesarean delivery 12.3-21.6%, operative vaginal delivery 10.7-15.4%, maternal hemorrhage 9.7-14.6%). Poor neonatal outcome varied with gestational age only for spontaneous labors (Apgar at 5 minutes less than 7 1.0-2.3%, pH less than 7.10 3.4-5.2%), whereas induction of labor was a risk factor for delivery complications (odds ratio 1.3-2.8), independent of gestational weeks.
Poor pregnancy outcomes vary with gestational age. Postterm pregnancy and induced labor are prognostic factors for poor outcome.
本研究旨在按孕周评估妊娠结局。另一个目的是评估自然分娩或引产组的结局。
这是一项对1990年至2001年在挪威一个明确界定区域内妊娠37周后分娩的单胎妊娠进行的前瞻性队列研究（N = 27,514）。使用了线性回归、卡方检验和多变量逻辑回归分析。
母体并发症随孕周而异，在39周时最低，过期妊娠时最高（剖宫产12.3 - 21.6%，阴道助产10.7 - 15.4%，母体出血9.7 - 14.6%）。仅自然分娩时不良新生儿结局随孕周而异（5分钟阿氏评分低于7分1.0 - 2.3%，pH值低于7.10 3.4 - 5.2%），而引产是分娩并发症的一个危险因素（比值比1.3 - 2.8），与孕周无关。
不良妊娠结局随孕周而异。过期妊娠和引产是不良结局的预后因素。
