Akinyinka O O, Falade A G, Ogbechie C O
Department of Paediatrics, University College Hospital, Ibadan, Nigeria.
Ann Trop Paediatr. 1990 Mar;10(1):85-8. doi: 10.1080/02724936.1990.11747414.
Prothrombin time, serum albumin, aminotransferases and liver size were evaluated in 40 consecutive cases of kwashiorkor. Eleven (27.5%) of the 40 patients died. Eight out of the 11 patients who died had a prolonged prothrombin time of more than 3 s above the control compared to only 4 out of the 29 who survived (p = 0.005). Mean serum aspartate aminotransferase (AST), alanine aminotransferase (ALT) albumin, globulin and liver size were abnormal but similar in both groups. These results may indicate a predictive mortality value of prothrombin time in kwashiorkor.
对40例恶性营养不良连续病例的凝血酶原时间、血清白蛋白、转氨酶和肝脏大小进行了评估。40例患者中有11例（27.5%）死亡。11例死亡患者中有8例凝血酶原时间延长，比对照组高出3秒以上，而29例存活患者中只有4例如此（p = 0.005）。两组的平均血清天冬氨酸转氨酶（AST）、丙氨酸转氨酶（ALT）、白蛋白、球蛋白和肝脏大小均异常，但相似。这些结果可能表明凝血酶原时间对恶性营养不良有预测死亡的价值。
