Bucher M B, Schorderet M
Naunyn Schmiedebergs Arch Pharmacol. 1975;288(1):103-7. doi: 10.1007/BF00501818.
Dopamine (0.5-100 muM) as well as apomorphine (1-100 muM) were found to be potent stimulators of adenylate cyclase in homogenates of rabbit retina. When compared with the dopamine-effect at 10 muM, half-stimulation was also obtained in response to noradrenaline or adrenaline, whereas isoprenaline or phenylephrine were ineffective. Furthermore, the dopamine-induced production of cyclic AMP wab blocked by chloropromazine and haloperidol. These data would suggest the occurrence of a specific "dopamine receptor" in the retina of the rabbit.
已发现多巴胺（0.5 - 100微摩尔）以及阿扑吗啡（1 - 100微摩尔）是兔视网膜匀浆中腺苷酸环化酶的有效刺激剂。与10微摩尔多巴胺的作用相比，去甲肾上腺素或肾上腺素也能产生半最大刺激效应，而异丙肾上腺素或去氧肾上腺素则无效。此外，氯丙嗪和氟哌啶醇可阻断多巴胺诱导的环磷酸腺苷生成。这些数据表明兔视网膜中存在一种特定的“多巴胺受体”。
