Opdam Helen I, Silvester William
Department of Intensive Care, Austin Health, Melbourne, VIC, Australia.
Med J Aust. 2006 Sep 4;185(5):250-4. doi: 10.5694/j.1326-5377.2006.tb00554.x.
To determine the potential for organ donation in 12 Victorian hospitals.
Prospective audit of all deaths in 12 major public hospitals in the state of Victoria between January 2002 and October 2004.
Number of organ donors and potential organ donors (patients with brain death or likely to progress to brain death within 24 hours if supportive treatment continued), requests for organ donation and consents. Unrealised potential donors (organ donation not requested) were categorised by an independent panel of intensivists as category A (brain death formally diagnosed); B (brain death not formally diagnosed but criteria likely to be fulfilled); and C (potential to progress to brain death within 24 hours).
There were 17,230 deaths, 280 potential organ donors and 220 requests for organ donation. The 60 unrealised potential organ donors were classified as category A (3), B (17) and C (40). Consent rate was 53% to 65%, depending on the definition of potential donor (categories A, B and C or category A only). Consent rate was lower when discussions about organ donation were held by trainees or registrars (21%) than when specialists were present (57%) (P = 0.004). A maximum practically achievable organ donation rate for Victoria was estimated to be 15 to 17 donors per million population (current rate, 9 per million population).
The potential for organ donation in Victoria is limited by a small organ donor pool. There is potential to increase the number of organ donors by increasing the consent rate (lower than expected from public surveys), the identification of potential organ donors (particularly those likely to progress to brain death if supportive treatment is continued), and requests for organ donation.
确定维多利亚州12家医院的器官捐献潜力。
对2002年1月至2004年10月期间维多利亚州12家主要公立医院的所有死亡病例进行前瞻性审计。
器官捐献者和潜在器官捐献者(脑死亡患者或如果继续进行支持性治疗在24小时内可能进展为脑死亡的患者)的数量、器官捐献请求及同意情况。未实现的潜在捐献者(未被请求进行器官捐献)由一组独立的重症监护专家分为A类(正式诊断为脑死亡);B类(未正式诊断为脑死亡但可能符合标准);C类(在24小时内有可能进展为脑死亡)。
共有17230例死亡病例,280名潜在器官捐献者,220次器官捐献请求。60名未实现的潜在器官捐献者被分类为A类(3名)、B类(17名)和C类(40名)。同意率为53%至65%,具体取决于潜在捐献者的定义(A、B、C类或仅A类)。当由实习医生或住院医生进行器官捐献讨论时同意率较低(21%),而有专家在场时同意率较高(57%)(P = 0.004)。估计维多利亚州实际可达到的最高器官捐献率为每百万人口15至17名捐献者(当前率为每百万人口9名)。
维多利亚州的器官捐献潜力因器官捐献者库较小而受到限制。通过提高同意率(低于公众调查预期)、识别潜在器官捐献者(特别是那些如果继续进行支持性治疗可能进展为脑死亡的患者)以及器官捐献请求,可以增加器官捐献者数量。