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孕产妇骨折与不良围产期结局的关联。

Association of maternal fractures with adverse perinatal outcomes.

作者信息

El Kady Dina, Gilbert William M, Xing Guibo, Smith Lloyd H

机构信息

Department of Obstetrics and Gynecology, University of California, Davis, Sacramento, CA, USA.

出版信息

Am J Obstet Gynecol. 2006 Sep;195(3):711-6. doi: 10.1016/j.ajog.2006.06.067.

Abstract

OBJECTIVE

We sought to assess the effects of fracture injuries on maternal and fetal/neonatal outcomes in a large obstetric population.

STUDY DESIGN

We performed a retrospective cohort study using a database in which maternal and neonatal hospital discharge summaries were linked with birth and death certificates to identify any relation between maternal fractures and maternal and perinatal morbidity. Fracture injuries and perinatal outcomes were identified with the use of the International Classification of Diseases, 9th revision, Clinical Modification codes. Outcomes were further subdivided on the basis of anatomic site of fracture.

RESULTS

A total of 3292 women with > or = 1 fractures were identified. Maternal mortality (odds ratio, 169 [95% CI, 83.2,346.4]) and morbidity (abruption and blood transfusion) rates were increased significantly in women who were delivered during hospitalization for their injury. Women who were discharged undelivered continued to have delayed morbidity, which included a 46% increased risk of low birth weight infants (odds ratio, 1.5 [95% CI, 1.3,1.7]) and a 9-fold increased risk of thrombotic events (odds ratio, 9.2 [95% CI, 1.3,65.7]) Pelvic fractures had the worst outcomes.

CONCLUSION

Fractures during pregnancy are an important marker for poor perinatal outcomes.

摘要

目的

我们试图评估骨折损伤对一大群产科人群中孕产妇及胎儿/新生儿结局的影响。

研究设计

我们进行了一项回顾性队列研究,使用一个数据库,其中孕产妇和新生儿出院总结与出生及死亡证明相链接,以确定孕产妇骨折与孕产妇及围产期发病率之间的任何关系。骨折损伤和围产期结局通过使用国际疾病分类第九版临床修订本编码来确定。结局根据骨折的解剖部位进一步细分。

结果

共识别出3292名有≥1处骨折的女性。因伤住院分娩的女性的孕产妇死亡率(比值比,169[95%可信区间,83.2,346.4])和发病率(胎盘早剥和输血)显著增加。未分娩出院的女性继续有延迟发病情况,包括低出生体重儿风险增加46%(比值比,1.5[95%可信区间,1.3,1.7])和血栓形成事件风险增加9倍(比值比,9.2[95%可信区间,1.3,65.7])。骨盆骨折的结局最差。

结论

孕期骨折是围产期结局不良的一个重要标志。

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