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超重及肥胖青少年的产科结局

Obstetric outcomes in overweight and obese adolescents.

作者信息

Sukalich Sara, Mingione Matthew J, Glantz J Christopher

机构信息

Department of Obstetrics and Gynecology, University of Rochester, Rochester, NY, USA.

出版信息

Am J Obstet Gynecol. 2006 Sep;195(3):851-5. doi: 10.1016/j.ajog.2006.06.070.

Abstract

OBJECTIVE

Obese adult pregnant women have increased rates of maternal and neonatal complications. Our objective was to examine adverse obstetric outcomes in overweight adolescent women.

STUDY DESIGN

In a retrospective case-control study of 4822 women who were < 19 years old, 3324 appropriate-weight subjects (body mass index, 18.5-24.9 kg/m2) and 1498 overweight subjects (body mass index, > or = 25 kg/m2) were compared. Frequencies and odds ratios for adverse maternal or neonatal events were computed.

RESULTS

Compared with appropriate-weight adolescents, primary cesarean delivery (odds ratio, 1.6; 95% CI, 1.4-1.9), failure to progress/cephalopelvic disproportion (odds ratio 1.6; 95% CI, 1.3-1.9), labor induction (odds ratio, 1.4; 95% CI, 1.3-1.7), pregnancy-induced hypertension (odds ratio, 1.8; 95% CI, 1.4-2.3), preeclampsia (odds ratio, 1.7; 95% CI, 1.2-2.4), and gestational diabetes mellitus (odds ratio, 3.0, 95% CI, 1.6-5.4) were significantly more common in overweight adolescents. Significant neonatal findings included an increased incidence of macrosomia (odds ratio, 1.6; 95% CI, 1.2-2.0) and a decreased incidence of low birth weight infants (odds ratio, 0.6; 95% CI, 0.4-0.8) and small for gestational age infants (odds ratio, 0.8; 95% CI, 0.7-1.0).

CONCLUSION

Overweight adolescent women are at increased risk for adverse neonatal and perinatal outcomes. With rates of overweight increasing overall, overweight in the gravid adolescent is a pressing perinatal and public health concern.

摘要

目的

肥胖成年孕妇出现孕产妇及新生儿并发症的几率增加。我们的目的是研究超重青少年女性的不良产科结局。

研究设计

在一项对4822名年龄小于19岁女性的回顾性病例对照研究中,比较了3324名体重正常的受试者(体重指数,18.5 - 24.9 kg/m²)和1498名超重受试者(体重指数,≥25 kg/m²)。计算了孕产妇或新生儿不良事件的发生率及比值比。

结果

与体重正常的青少年相比,超重青少年中剖宫产(比值比,1.6;95%可信区间,1.4 - 1.9)、产程停滞/头盆不称(比值比1.6;95%可信区间,1.3 - 1.9)、引产(比值比,1.4;95%可信区间,1.3 - 1.7)、妊娠期高血压(比值比,1.8;95%可信区间,1.4 - 2.3)、先兆子痫(比值比,1.7;95%可信区间,1.2 - 2.4)和妊娠期糖尿病(比值比,3.0,95%可信区间,1.6 - 5.4)更为常见。显著的新生儿发现包括巨大儿发生率增加(比值比,1.6;95%可信区间,1.2 - 2.0)以及低出生体重儿(比值比,0.6;95%可信区间,0.4 - 0.8)和小于胎龄儿(比值比,0.8;95%可信区间,0.7 - 1.0)发生率降低。

结论

超重青少年女性出现不良新生儿及围产期结局的风险增加。随着总体超重率上升,妊娠青少年超重是一个紧迫的围产期及公共卫生问题。

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