Richter P, Krafft W, Müller U, Brückmann D, Homann S, König E M, Lotze P, Morack G, Neubert S, Nöschel H
Arbeitsgruppe Chemotherapie in der Gynäkologie der DDR.
Zentralbl Gynakol. 1990;112(7):421-9.
The efficiency of cis Platin (DDP) alone and in combination with Adriamycine (ADM) and Cyclophosphamid (CTX) were evaluated in a prospective randomized trial containing 173 pat. suffering from advanced ovarian cancer (FIGO III/IV). Therapeutic schedule and results: (table; see text) The most side effects concerned vomiting (WHO Grad 2) in 90%, nausea (WHO Grad 2) in 95% and alopecia in 50% out of all pat.
在一项包含173例晚期卵巢癌(国际妇产科联盟III/IV期)患者的前瞻性随机试验中,评估了顺铂(DDP)单独使用以及与阿霉素(ADM)和环磷酰胺(CTX)联合使用的疗效。治疗方案和结果:(表格;见正文)在所有患者中,最常见的副作用是呕吐(世界卫生组织2级)发生率为90%,恶心(世界卫生组织2级)发生率为95%,脱发发生率为50%。