肝硬化门静脉高压症手术治疗后纤连蛋白水平正常。
Normal fibronectin levels after surgical treatment of portal hypertension in liver cirrhosis.
作者信息
De Angelis V, Zambon M, Toffolo L, Voltan G P, Orazi B M, Santarossa L, Donada C, Zuin R
机构信息
Cattedra di Semeiotica Medica II, Universitá di Padova, Italy.
出版信息
Folia Haematol Int Mag Klin Morphol Blutforsch. 1990;117(1):89-93.
We found a significantly higher plasma fibronectin concentration in a group of nine cirrhotic patients who underwent surgical treatment for portal hypertension (either shunting and non shunting procedures) when compared to twenty non operated patients. Significantly shorter prothrombin time and activated partial thromboplastin time in the operated patients were found as well. These results might be related to an increased breakdown of fibronectin during consumption coagulopathy taking place in the extended collaterals and reversed in part by surgical treatment of portal hypertension complicating liver cirrhosis.
我们发现，与20名未接受手术的患者相比，一组9名因门静脉高压接受手术治疗（分流术和非分流术）的肝硬化患者血浆纤连蛋白浓度显著更高。此外，还发现手术患者的凝血酶原时间和活化部分凝血活酶时间明显缩短。这些结果可能与在扩张的侧支循环中发生的消耗性凝血病期间纤连蛋白分解增加有关，而肝硬化合并门静脉高压的手术治疗部分逆转了这种情况。
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