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[癌症疼痛门诊患者的患者自控镇痛(PCA)。1692个治疗日的分析]

[Patient-controlled analgesia (PCA) in outpatients with cancer pain. Analysis of 1,692 treatment days].

作者信息

Schiessl C, Bidmon J, Sittl R, Griessinger N, Schüttler J

机构信息

Schmerzambulanz der Anästhesiologischen Klinik, Universitätsklinikum, Erlangen.

出版信息

Schmerz. 2007 Feb;21(1):35-8, 40-2. doi: 10.1007/s00482-006-0500-9.

Abstract

INTRODUCTION

In the home-care setting, cancer pain patients in need of parenteral analgesia have to be switched to patient-controlled analgesia using portable pumps. But there is a paucity on data on the logistic requirements or the success rate of such a cost-intensive therapy performed by specialized home-care services.

METHODS

In a retrospective study we analyzed data on care intensity, logistics and outcome of 46 consecutive palliative cancer patients with patient-controlled analgesia (PCA) in a home-care setting.

RESULTS

On days 1, 2, and 3 of PCA the switch to parenteral analgesia resulted in a significant increase of the median daily opioid dose in comparison to the dose just prior to PCA. Concurrently, pain scores were significantly reduced. The median duration of PCA was 25 days (range 2-189 days). On average, each patient was seen by the home-care team every 7.4 days. The median duration of the home visits was 60 min (range, 10-190 min). Of the visits 20% were unscheduled, most of these visits being due to problems regarding analgesia. Most patients died at home. Insufficient analgesia required prefinal hospitalization in only a single case.

CONCLUSION

If the indications are correct, intravenous PCA for palliative cancer pain patients results in higher opioid consumption and better pain control. Home-care PCA requires a lot of human and financial resources, but pain-related hospitalization can be prevented.

摘要

引言

在家庭护理环境中,需要胃肠外镇痛的癌症疼痛患者必须改用便携式泵进行患者自控镇痛。但是,关于由专业家庭护理服务机构提供的这种成本高昂的治疗的后勤需求或成功率的数据却很少。

方法

在一项回顾性研究中,我们分析了46例在家庭护理环境中接受患者自控镇痛(PCA)的连续性姑息性癌症患者的护理强度、后勤情况及治疗结果的数据。

结果

在PCA治疗的第1、2和3天,与PCA治疗前的剂量相比,改用胃肠外镇痛后每日阿片类药物剂量中位数显著增加。同时,疼痛评分显著降低。PCA的中位持续时间为25天(范围2 - 189天)。家庭护理团队平均每7.4天看望每位患者一次。家访的中位持续时间为60分钟(范围10 - 190分钟)。其中20%的家访是临时安排的,大多数此类家访是由于镇痛相关问题。大多数患者在家中死亡。仅1例患者因镇痛不足在临终前住院。

结论

如果适应症正确,姑息性癌症疼痛患者静脉PCA会导致更高的阿片类药物消耗量和更好的疼痛控制。家庭护理PCA需要大量人力和财力资源,但可以预防与疼痛相关的住院治疗。

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