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哪种抗精神病药物作为精神分裂症的首选药物?2005年荷兰精神分裂症多学科指南与2005年药物治疗指南、荷兰国家健康保险系统处方集的对比

[Which antipsychotic as first choice in schizophrenia? The Dutch Multidisciplinary Guideline for Schizophrenia 2005 versus the Pharmacotherapy Compass 2005, the Dutch National Health Insurance System Formulary].

作者信息

Harms H H

机构信息

De Geestgronden te Bennebroeck.

出版信息

Tijdschr Psychiatr. 2006;48(1):45-51.

PMID:16955985
Abstract

The pharmacotherapy advice contained in the 'Multidisciplinaire Richtlijn Schizofrenie 2005' (abbreviated to MDRS 2005 and translated as the Dutch Multidisciplinary Schizophrenia Guideline) is compared with the advice given in the 'Farmacotherapeutisch Kompas 2005' (abbreviated to FTK 2005 and translated as the Pharmacotherapy Compass 2005) and with international guidelines. FTK 2005, which is the Dutch National Health Insurance Formularium, recommends that treatment should start with a conventional (first-generation) antipsychotic, namely haloperidol. International guidelines, however, advise starting with an atypical (second-generation) antipsychotic. MDRS 2005 suggests that the pros and cons of the medication should be discussed with the patient and that the choice of drug should be based on the outcome of this discussion. Ifthat discussion becomes problematical then, according to MD RS 2005, it is advisable

摘要

将《2005年精神分裂症多学科指南》(简称为MDRS 2005,译为荷兰多学科精神分裂症指南)中包含的药物治疗建议,与《2005年药物治疗指南》(简称为FTK 2005,译为《2005年药物治疗指南》)以及国际指南中的建议进行比较。作为荷兰国家医疗保险处方集的FTK 2005建议,治疗应从传统(第一代)抗精神病药物开始,即氟哌啶醇。然而,国际指南建议从非典型(第二代)抗精神病药物开始。MDRS 2005建议应与患者讨论药物的利弊,并且药物的选择应基于该讨论的结果。如果该讨论出现问题,那么根据MDRS 2005,建议……

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