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Human cytomegalovirus tropism for endothelial cells: not all endothelial cells are created equal.

作者信息

Jarvis Michael A, Nelson Jay A

机构信息

Vaccine and Gene Therapy Institute, Oregon Health Science University, 3181 SW Sam Jackson Park Road, Portland, OR 97239, USA.

出版信息

J Virol. 2007 Mar;81(5):2095-101. doi: 10.1128/JVI.01422-06. Epub 2006 Sep 6.

DOI:10.1128/JVI.01422-06
PMID:16956936
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1865914/
Abstract
摘要

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本文引用的文献

1
Human cytomegalovirus attenuates interleukin-1beta and tumor necrosis factor alpha proinflammatory signaling by inhibition of NF-kappaB activation.人巨细胞病毒通过抑制核因子κB激活来减弱白细胞介素-1β和肿瘤坏死因子α的促炎信号传导。
J Virol. 2006 Jun;80(11):5588-98. doi: 10.1128/JVI.00060-06.
2
Human cytomegalovirus UL131A, UL130 and UL128 genes are highly conserved among field isolates.人巨细胞病毒UL131A、UL130和UL128基因在野外分离株中高度保守。
Arch Virol. 2006 Jun;151(6):1225-33. doi: 10.1007/s00705-005-0696-5. Epub 2005 Dec 29.
3
Human cytomegalovirus entry into epithelial and endothelial cells depends on genes UL128 to UL150 and occurs by endocytosis and low-pH fusion.人巨细胞病毒进入上皮细胞和内皮细胞取决于UL128至UL150基因,通过内吞作用和低pH融合发生。
J Virol. 2006 Jan;80(2):710-22. doi: 10.1128/JVI.80.2.710-722.2006.
4
Human cytomegalovirus virion protein complex required for epithelial and endothelial cell tropism.上皮细胞和内皮细胞嗜性所需的人巨细胞病毒病毒体蛋白复合物。
Proc Natl Acad Sci U S A. 2005 Dec 13;102(50):18153-8. doi: 10.1073/pnas.0509201102. Epub 2005 Nov 30.
5
Broadly targeted human cytomegalovirus-specific CD4+ and CD8+ T cells dominate the memory compartments of exposed subjects.广泛靶向的人巨细胞病毒特异性CD4+和CD8+ T细胞在暴露个体的记忆细胞区室中占主导地位。
J Exp Med. 2005 Sep 5;202(5):673-85. doi: 10.1084/jem.20050882.
6
Human cytomegalovirus UL131 open reading frame is required for epithelial cell tropism.人巨细胞病毒UL131开放阅读框是上皮细胞嗜性所必需的。
J Virol. 2005 Aug;79(16):10330-8. doi: 10.1128/JVI.79.16.10330-10338.2005.
7
Human cytomegalovirus UL130 protein promotes endothelial cell infection through a producer cell modification of the virion.人巨细胞病毒UL130蛋白通过对病毒体的生产者细胞修饰促进内皮细胞感染。
J Virol. 2005 Jul;79(13):8361-73. doi: 10.1128/JVI.79.13.8361-8373.2005.
8
Dendritic-cell infection by human cytomegalovirus is restricted to strains carrying functional UL131-128 genes and mediates efficient viral antigen presentation to CD8+ T cells.人巨细胞病毒对树突状细胞的感染仅限于携带功能性UL131 - 128基因的毒株,并介导病毒抗原向CD8 + T细胞的有效呈递。
J Gen Virol. 2005 Feb;86(Pt 2):275-284. doi: 10.1099/vir.0.80474-0.
9
Human cytomegalovirus proteins encoded by UL37 exon 1 protect infected fibroblasts against virus-induced apoptosis and are required for efficient virus replication.由UL37外显子1编码的人巨细胞病毒蛋白可保护受感染的成纤维细胞免受病毒诱导的细胞凋亡,并且是高效病毒复制所必需的。
J Gen Virol. 2004 Dec;85(Pt 12):3555-3567. doi: 10.1099/vir.0.80379-0.
10
A cyclooxygenase-2 homologue encoded by rhesus cytomegalovirus is a determinant for endothelial cell tropism.恒河猴巨细胞病毒编码的一种环氧化酶-2同源物是内皮细胞嗜性的决定因素。
J Virol. 2004 Nov;78(22):12529-36. doi: 10.1128/JVI.78.22.12529-12536.2004.