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胰腺内分泌肿瘤中柠檬酸镓-67的强烈积聚。

Intense accumulation of gallium-67 citrate in pancreatic endocrine tumor.

作者信息

Watanabe Rieko, Iizuka Harunao, Kaira Kyoichi, Mori Takanori, Takise Atsushi, Ito Jun, Motegi Atsushi, Onozato Yasuhiro, Ishihara Hiroshi

机构信息

Department of Respiratory Medicine, Maebashi Red Cross Hospital, Maebashi, Gunma 371-0014, Japan.

出版信息

Radiat Med. 2006 Jul;24(6):456-8. doi: 10.1007/s11604-006-0043-0.

DOI:10.1007/s11604-006-0043-0
PMID:16958428
Abstract

We report intense accumulation of gallium-67 (Ga-67) citrate in a pancreatic endocrine tumor. A 69-year-old woman was admitted because of cough, fever, and weight loss. An abdominal enhanced computed tomography (CT) scan revealed a large tumor located between the liver and pancreas as well as swollen paraaortic lymph nodes. Whole-body scintigraphy with Ga-67 revealed intense accumulation in the upper abdomen corresponding to the mass, as well as in the midabdomen and the mediastinal lesion. Percutaneous needle biopsy was performed, and the diagnosis was adenocarcinoma of the pancreas. The patient's condition deteriorated, and she died 2 months after admission. The pathological examination at autopsy revealed a pancreatic endocrine tumor. No report has described findings of Ga-67 citrate scintigraphy of pancreatic endocrine tumors. Pancreatic endocrine tumor should be included in a differential diagnosis when such scintigraphic findings are encountered.

摘要

我们报告了1例胰腺内分泌肿瘤中柠檬酸镓-67(Ga-67)的强烈聚集。一名69岁女性因咳嗽、发热和体重减轻入院。腹部增强计算机断层扫描(CT)显示肝脏和胰腺之间有一个大肿瘤以及主动脉旁淋巴结肿大。Ga-67全身闪烁显像显示上腹部与肿块相对应处、中腹部及纵隔病变处有强烈聚集。进行了经皮穿刺活检,诊断为胰腺癌。患者病情恶化,入院2个月后死亡。尸检病理检查显示为胰腺内分泌肿瘤。尚无关于胰腺内分泌肿瘤Ga-67柠檬酸盐闪烁显像结果的报道。当遇到此类闪烁显像结果时,胰腺内分泌肿瘤应纳入鉴别诊断。

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本文引用的文献

1
Position of nuclear medicine techniques in the diagnostic work-up of neuroendocrine tumors.核医学技术在神经内分泌肿瘤诊断检查中的地位。
Q J Nucl Med Mol Imaging. 2004 Jun;48(2):150-63.
2
Intense accumulation of Ga-67 citrate in solid and cystic tumors of the pancreas.胰腺实性和囊性肿瘤中柠檬酸镓-67的大量聚集。
Clin Nucl Med. 2002 Sep;27(9):663-4. doi: 10.1097/00003072-200209000-00013.
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MRI of pancreatic neuroendocrine tumours.胰腺神经内分泌肿瘤的磁共振成像
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Nonfunctioning islet cell tumors of the pancreas: a difficult diagnosis but one worth the effort.胰腺无功能性胰岛细胞瘤:诊断困难,但值得努力。
Am Surg. 1997 Jul;63(7):573-7; discussion 577-8.
5
Intense Ga-67 uptake in adenosquamous carcinoma of the pancreas.胰腺腺鳞癌中镓-67摄取增强。
Ann Nucl Med. 1997 Feb;11(1):41-3. doi: 10.1007/BF03164758.
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Mechanism of gallium-67 accumulation in tumors.
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Avid accumulation of Ga-67 citrate in adenocarcinoma of pancreas.胰腺腺癌中柠檬酸镓-67的大量积聚。
Clin Nucl Med. 1989 Nov;14(11):843-5. doi: 10.1097/00003072-198911000-00015.