Benke T, Andree B, Hittmair M, Gerstenbrand F
Klinik für Neurologie Innsbruck.
Fortschr Neurol Psychiatr. 1990 Jun;58(6):215-23. doi: 10.1055/s-2007-1001185.
This review analyzes the spectrum of language deficits commonly encountered in dementia. A specific communication profile is found in dementia of the "cortical" type, such as Alzheimer's disease. With advancing disease lexical, comprehension and pragmatic functions deteriorate, whereas syntax and phonology tend to be preserved. This pattern bears some resemblance to aphasia types like transcortical and Wernicke's aphasia, however, a much broader range of communicative functions is impaired in Alzheimer's disease than in aphasia. Differentiation of dementia and aphasia, especially in elderly patients requires careful neuropsychological assessment of language, memory and other psychological functions. "Subcortical" dementia commonly presents with dysarthria as the leading symptom and linguistic impairment is rarely of crucial importance until late stages. Thus, the interetiologic dissociation of language and speech impairment can be used for dementia differentiation. Aphasia batteries are not sufficient to comprehend the range of language deficits in demented patients. Testing the communication impairment in dementia requires specific tasks for spontaneous speech, naming, comprehension, reading, writing, repetition and motor speech functions. Tasks for verbal learning and metalinguistic abilities should also be performed. Language deficits are frequent initial symptoms of dementia, thus language assessment may be of diagnostic relevance. Many data support the concept that the communication deficit in dementia results from a particular impairment of semantic memory.
本综述分析了痴呆症中常见的语言缺陷范围。在“皮质”型痴呆症(如阿尔茨海默病)中发现了一种特定的交流特征。随着疾病进展,词汇、理解和语用功能会恶化,而句法和语音往往得以保留。这种模式与经皮质性失语和韦尼克失语等失语症类型有一些相似之处,然而,与失语症相比,阿尔茨海默病中受损的交流功能范围要广泛得多。区分痴呆症和失语症,尤其是在老年患者中,需要对语言、记忆和其他心理功能进行仔细的神经心理学评估。“皮质下”痴呆症通常以构音障碍为主要症状,直到晚期语言障碍才很少具有关键重要性。因此,语言和言语障碍的病因间分离可用于痴呆症的鉴别。失语症成套测验不足以理解痴呆患者语言缺陷的范围。测试痴呆症中的交流障碍需要针对自发言语、命名、理解、阅读、写作、复述和运动言语功能的特定任务。还应进行言语学习和元语言能力的测试。语言缺陷是痴呆症常见的初始症状,因此语言评估可能具有诊断意义。许多数据支持这样的概念,即痴呆症中的交流缺陷是由语义记忆的特定损伤导致的。