Hiesmayr Michael J
Department of Cardiac-Thoracic-Vascular Anaesthesia & Intensive Care Medicine, Medical University Vienna, Vienna, Austria.
Semin Cardiothorac Vasc Anesth. 2006 Sep;10(3):220-3. doi: 10.1177/1089253206291139.
Hyperglycemia is a frequent observation during acute illness such as myocardial infarction and after major surgery. The proportion of patients with hyperglycemia may be as high as 95% to 100% after cardiac surgery. This stress-induced hyperglycemia has a detrimental effect on outcome after myocardial infarction and cardiac surgery. Mortality may increase by a factor of 4, especially in non-diabetic patients. Control of hyperglycemia to normalize blood glucose is associated with a clear clinical benefit. This effect is most beneficial in nondiabetic patients with hyperglycemia. The exact target level of glycemia is still a matter of investigation, but normalization to values between 80 and 125 mg/dL is probably optimal.
高血糖在急性疾病如心肌梗死期间以及大手术后很常见。心脏手术后高血糖患者的比例可能高达95%至100%。这种应激性高血糖对心肌梗死和心脏手术后的预后有不利影响。死亡率可能会增加4倍，尤其是在非糖尿病患者中。将高血糖控制到血糖正常水平具有明显的临床益处。这种效果在患有高血糖的非糖尿病患者中最为有益。血糖的确切目标水平仍在研究中，但将血糖水平恢复到80至125毫克/分升之间可能是最佳的。
