Geppert Christian, Dreher Wolfgang, Althaus Matthias, Leibfritz Dieter
Universitä Bremen, FB 2, Chemie, Leobener Street NW2/C, 28334, Bremen, Germany.
MAGMA. 2006 Sep;19(4):196-201. doi: 10.1007/s10334-006-0047-x. Epub 2006 Sep 8.
Recently, new methods for fast (1)H spectroscopic imaging based on the condition of steady state free precession (SSFP) were introduced to achieve a high signal-to-noise ratio at short minimum measurement times. In this work, a major improvement is presented to overcome a crucial drawback in some of the former sequences: the lack of spatial selectivity. Good spectral selectivity at very high sampling efficiency can be achieved by using spectral-spatial RF pulses, and combined with localised shimming. Results are shown from both phantom experiments and in vivo studies on the rat brain acquired at 4.7 T.
最近,基于稳态自由进动(SSFP)条件的快速氢质子光谱成像新方法被引入,以在最短测量时间内实现高信噪比。在这项工作中,提出了一项重大改进,以克服一些先前序列中的一个关键缺点:缺乏空间选择性。通过使用频谱空间射频脉冲,并结合局部匀场,可以在非常高的采样效率下实现良好的光谱选择性。展示了在4.7T下对大鼠脑进行的体模实验和体内研究的结果。