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肾性高血压大鼠和自发性高血压大鼠体内的矿物质

Minerals in renal and SHR hypertensive rats.

作者信息

Loyke H F

机构信息

Cleveland Research Institute, Saint Vincent Charity Hospital and Health Center, OH 44115.

出版信息

Biol Trace Elem Res. 1990 Apr;25(1):47-50. doi: 10.1007/BF02990263.

Abstract

References to individual trace minerals in hypertensive rats have been made; however, data on multiple minerals in SHR hypertensive rats is lacking. The purpose of this study was to investigate five trace minerals in normotensive, chronic renal and SHR hypertensive rats. Blood samples were drawn to measure serum levels of Ca, Fe, K, Mg, and Na. Serum K values were elevated in the chronic renal hypertensive animals. Iron levels were decreased in both the renal and SHR hypertensive animals. No difference was observed in levels of Ca, Mg, and Na between normotensive and chronic renal or SHR hypertensive rats. Further study of multiple trace minerals in experimental hypertension is recorded in order to extend these deviations.

摘要

已有关于高血压大鼠体内个别微量矿物质的研究报道;然而,关于自发性高血压大鼠(SHR)体内多种矿物质的数据尚缺。本研究旨在调查正常血压大鼠、慢性肾性高血压大鼠和SHR高血压大鼠体内的五种微量矿物质。采集血样以测量血清中钙、铁、钾、镁和钠的水平。慢性肾性高血压动物的血清钾值升高。肾性高血压动物和SHR高血压动物的铁水平均降低。正常血压大鼠与慢性肾性高血压大鼠或SHR高血压大鼠之间的钙、镁和钠水平未观察到差异。记录了对实验性高血压中多种微量矿物质的进一步研究,以扩大这些偏差。

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