Buckley Peter F
Department of Psychiatry and Health Behavior, Medical College of Georgia, Augusta, GA 30912, USA.
J Clin Psychiatry. 2006;67 Suppl 7:5-9.
The co-occurrence of a severe mental illness and a substance use or abuse disorder is common in the United States as well as internationally and could be considered as more the expectation than the exception when assessing patients with serious mental illness. Substance use disorders can occur at any phase of the mental illness, perhaps even inducing psychosis. Causes of this comorbidity may include self-medication, genetic vulnerability, environment or lifestyle, underlying shared origins, and/or a common neural substrate. The consequences of dual diagnosis include poor medication compliance, physical comorbidities and poor health, poor self-care, increased suicide risk or aggression, increased sexual behavior, and possible incarceration. All of these factors contribute to a greater health burden, which reduces the health care system's capacity to adequately treat patients. Therefore, screening, assessment, and integrated treatment plans for dual diagnosis that can address both the addiction disorder and the mental illness are recommended in order to provide accurate treatment, after-care, and other health care to accommodate patients' social and vocational needs.
严重精神疾病与物质使用或滥用障碍同时出现的情况在美国以及国际上都很常见,在评估患有严重精神疾病的患者时,这可能被视为一种常态而非例外。物质使用障碍可能发生在精神疾病的任何阶段,甚至可能诱发精神病。这种共病的原因可能包括自我用药、遗传易感性、环境或生活方式、潜在的共同起源和/或共同的神经基质。双重诊断的后果包括药物治疗依从性差、身体共病和健康状况不佳、自我护理差、自杀风险或攻击性增加、性行为增加以及可能被监禁。所有这些因素都会导致更大的健康负担,从而降低医疗保健系统充分治疗患者的能力。因此,建议制定针对双重诊断的筛查、评估和综合治疗计划,以同时解决成瘾障碍和精神疾病,从而提供准确的治疗、后续护理和其他医疗保健服务,以满足患者的社会和职业需求。