Parry Charles D, Blank Michael B, Pithey Anne L
Alcohol and Drug Abuse Research Unit, Medical Research Council, Tygerberg, South Africa.
Curr Opin Psychiatry. 2007 May;20(3):235-41. doi: 10.1097/YCO.0b013e3280ebb5f0.
This article discusses current knowledge regarding the threat of HIV among persons with mental illness and substance abuse, and strategies for reducing this threat. It contains a review of the prevalence and consequences of dual/triple diagnosis, HIV risk behaviour and current HIV risk-reduction interventions among persons with dual diagnosis and interventions for triply diagnosed individuals.
Many persons with dual diagnosis remain undetected and there is a high prevalence of sexual risk behaviours among persons with dual diagnosis. Case management and supportive housing programmes are feasible options for the delivery of HIV risk-reduction interventions among such patients, and the adaptation of integrated behavioural treatment interventions can improve behavioural and healthcare utilization outcomes.
The developing world continues to see an escalation in HIV incidence. A more complete understanding of mental health, substance use and HIV serostatus interactions is needed to serve vulnerable populations. Mental health status not only mediates HIV risk behaviours, but positive serostatus has various effects on mental health. Co-morbid substance abuse is common among HIV-positive individuals with mental illness, resulting in serious adverse effects. Separate services for individuals with co-occurring substance abuse are less effective than integrated treatment programmes.
本文讨论了关于精神疾病和药物滥用患者中艾滋病毒威胁的现有知识,以及降低这种威胁的策略。它回顾了双重/三重诊断的患病率和后果、艾滋病毒风险行为,以及双重诊断患者目前的艾滋病毒风险降低干预措施和三重诊断个体的干预措施。
许多双重诊断患者未被发现,双重诊断患者中性风险行为的患病率很高。病例管理和支持性住房项目是为这类患者提供艾滋病毒风险降低干预措施的可行选择,综合行为治疗干预措施的调整可以改善行为和医疗保健利用结果。
发展中世界的艾滋病毒发病率持续上升。需要更全面地了解心理健康、药物使用和艾滋病毒血清学状态之间的相互作用,以便为弱势群体提供服务。心理健康状况不仅介导艾滋病毒风险行为,而且阳性血清学状态对心理健康有多种影响。合并药物滥用在患有精神疾病的艾滋病毒阳性个体中很常见,会导致严重的不良影响。为同时存在药物滥用问题的个体提供单独服务的效果不如综合治疗项目。