儿童系统性红斑狼疮中的自身免疫性血小板减少症：替代治疗方式
Autoimmune thrombocytopenia in pediatric systemic lupus erythematosus: alternative therapeutic modalities.
作者信息
Lipnick R N, Tsokos G C, Bray G L, White P H
机构信息
Department of Pediatrics, George Washington University Medical School, Washington, D.C. 20010.
出版信息
Clin Exp Rheumatol. 1990 May-Jun;8(3):315-9.
PMID:1696192
Abstract
Three patients with pediatric systemic lupus erythematosus (PSLE) and autoimmune thrombocytopenia (AT), who developed unacceptable side effects (pseudotumor cerebri, hypertension, excessive weight gain) from treatment with steroids, were treated successfully with vincristine (2 patients) or intravenous immunoglobulin (1 patient). All patients remained off steroids without any complications for 11 to 23 months.
摘要
三名患有儿童系统性红斑狼疮（PSLE）和自身免疫性血小板减少症（AT）的患者，因使用类固醇治疗出现了不可接受的副作用（假性脑瘤、高血压、体重过度增加），分别接受长春新碱（2例患者）或静脉注射免疫球蛋白（1例患者）治疗后获得成功。所有患者停用类固醇后11至23个月均未出现任何并发症。
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