Vyas Himeshkumar, Ackerman Michael J
Division of Pediatric Cardiology, Department of Pediatric and Adolescent Medicine, Mayo Clinic College of Medicine, Rochester, MN 55905, USA.
J Electrocardiol. 2006 Oct;39(4 Suppl):S107-13. doi: 10.1016/j.jelectrocard.2006.05.013. Epub 2006 Sep 7.
Epinephrine QT stress testing is an effective diagnostic tool to unmask concealed Long QT Syndrome (LQTS), particularly type 1 LQTS (LQT1). Unique responses have also been observed in patients with LQT2 and LQT3, making this test invaluable in the diagnostic work-up of LQTS. This article reviews the epinephrine QT stress test, explains the pathological basis of differential responses among patients and healthy individuals, and describes the methodology for conducting the test and the interpretation of the responses. We have also attempted to highlight the differences between the two major LQTS epinephrine QT stress test protocols, the Mayo protocol and the Shimizu protocol.
肾上腺素激发试验是一种有效的诊断工具,可揭示隐匿性长QT综合征(LQTS),尤其是1型长QT综合征(LQT1)。在LQT2和LQT3患者中也观察到了独特的反应,这使得该试验在LQTS的诊断检查中具有重要价值。本文回顾了肾上腺素激发试验,解释了患者与健康个体之间差异反应的病理基础,并描述了该试验的实施方法及反应解读。我们还试图突出两种主要的LQTS肾上腺素激发试验方案——梅奥方案和清水方案之间的差异。