从以DNA为中心的视角审视蛋白质-DNA复合物。

A DNA-centric look at protein-DNA complexes.

作者信息

Sen Taner Z, Kloczkowski Andrzej, Jernigan Robert L

出版信息

Structure. 2006 Sep;14(9):1341-2. doi: 10.1016/j.str.2006.08.003.

DOI:10.1016/j.str.2006.08.003

Abstract

The availability of many DNA-protein structures makes their classification timely and important. In this issue of Structure, the method of Akinori Sarai and his collaborators (Prabakaran et al., 2006) utilizes aspects of the binding interactions and DNA properties to identify seven clusters of structures with a classification scheme that differs significantly from previous approaches.

摘要

许多DNA-蛋白质结构的可得性使得对它们进行分类既及时又重要。在本期《结构》杂志中，酒井章典及其合作者（普拉巴卡兰等人，2006年）的方法利用了结合相互作用和DNA特性的各个方面，通过一种与以往方法有显著不同的分类方案来识别七类结构。