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乳腺癌女性患者的失眠及其治疗

Insomnia and its treatment in women with breast cancer.

作者信息

Fiorentino Lavinia, Ancoli-Israel Sonia

机构信息

SDSU/UCSD Joint Doctoral Program in Clinical Psychology, VASDHS, San Diego, CA 92161, USA.

出版信息

Sleep Med Rev. 2006 Dec;10(6):419-29. doi: 10.1016/j.smrv.2006.03.005. Epub 2006 Sep 11.

Abstract

Insomnia is a common complaint in breast cancer patients and has been shown to have a host of psychological and medical correlates and consequences. Typically insomnia is treated pharmacologically, however more recent findings from randomized controlled clinical trials support the use of cognitive behavioral therapies. The aim of this article is to review the empirically supported breast cancer literature on insomnia, briefly present and explain the insomnia treatment options available, and extrapolate research guidelines for future directions in this growing field. Behavioral therapeutic approaches for insomnia seem particularly suitable to use in the breast cancer populations because they have lower risk of interacting with the cancer treatment, do not burden the patients with additional pharmacological treatments, and can target the treatment towards ameliorating specific symptoms, like fatigue, that are characteristic in this population. However, there is a need for replication of efficacy studies of cognitive behavioral treatments for insomnia in breast cancer, as well as studies investigating vulnerability, risk and protective factors that might ultimately lead to insomnia prevention programs for use in this population.

摘要

失眠是乳腺癌患者常见的主诉,并且已被证明存在一系列心理和医学方面的关联及后果。通常情况下,失眠采用药物治疗,然而随机对照临床试验的最新研究结果支持使用认知行为疗法。本文旨在综述关于乳腺癌患者失眠的实证研究文献,简要介绍并解释现有的失眠治疗方案,并推断该新兴领域未来研究方向的指导方针。失眠的行为治疗方法似乎特别适合用于乳腺癌人群,因为它们与癌症治疗相互作用的风险较低,不会给患者增加额外的药物治疗负担,并且可以针对改善该人群特有的特定症状(如疲劳)进行治疗。然而,需要重复进行针对乳腺癌患者失眠的认知行为治疗疗效研究,以及调查可能最终导致该人群失眠预防方案的易感性、风险和保护因素的研究。

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