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[重症监护病房的医院获得性肺炎。波兰医院感染学会的现行医院感染监测项目]

[Hospital acquired pneumonia at the intensive care units. The active nosocomial infections surveillance programme of Polish Society of Hospital Infections].

作者信息

Wójkowska-Mach Jadwiga, Bulanda Małgorzata, Rózańska Anna, Heczko Piotr B

机构信息

Katedra Mikrobiologii Uniwersytet Jagiellońiski Collegium Medicum.

出版信息

Przegl Epidemiol. 2006;60(2):225-35.

PMID:16964673
Abstract

Currently, the Polish Society of Hospital Infections is coordinating a national program of active surveillance of nosocomial infections. One of its elements is the control of hospital acquired pneumonia (PNEU) on Intensive Care Units. This paper analyzes the epidemiology and etiology of hospital acquired pneumonia (PNEU) at the Intensive Care Units (ICU). Surveillance was conducted by means of an active method of detection and registration of infections by the Infection Control Team (ICT) in cooperation with the unit personnel, in accordance with CDC definitions, during the years: 2002-2003 IN 8 Polish ICU -surgical, medical and mixed. A total of 11 587 hospitalized patients from ICU were covered by the program, with 191 confirmed cases of PNEU. The average cumulative incidence of PNEU was 5.6% (median 4.9%), incidence density of Ventilator Associated Pneumonia (VAP) on average reached 17.9 per thousand (median 18.8 per thousand); mortality of patients with PNEU totaled 12.6% and for patients on ventilator and with coexisting infections 15.0% and 20%, respectively--it wasn't high enough to be statistically significant. Dominant etiologic factors of hospital acquired pneumonia in patients with a risk factor were Pseudomonas aeruginosa and Escherichia coli Methicillin-resistant Staphylococcus aureus(MRSA) comprised 21.1% of isolated S. aureus strains. The analyzes in this paper show that it's possible to effectively implement uniform methods of detection, qualification and analysis in relatively new settings at Polish hospitals, where tools of modern hospital epidemiology are only used since the mid 90-ties.

摘要

目前,波兰医院感染学会正在协调一项全国性的医院感染主动监测计划。其中一项内容是对重症监护病房的医院获得性肺炎(PNEU)进行控制。本文分析了重症监护病房(ICU)医院获得性肺炎(PNEU)的流行病学和病因。监测是通过感染控制团队(ICT)与科室人员合作,按照美国疾病控制与预防中心(CDC)的定义,采用主动检测和登记感染的方法进行的,时间跨度为2002年至2003年,涉及波兰8个ICU——外科、内科和综合科室。该计划共覆盖了11587名入住ICU的住院患者,确诊PNEU病例191例。PNEU的平均累积发病率为5.6%(中位数为4.9%),呼吸机相关性肺炎(VAP)的发病密度平均达到每千例17.9例(中位数为每千例18.8例);PNEU患者的死亡率总计为12.6%,使用呼吸机且合并感染的患者死亡率分别为15.0%和20%——该死亡率未高到具有统计学意义。有危险因素的患者医院获得性肺炎的主要病因是铜绿假单胞菌和大肠埃希菌,耐甲氧西林金黄色葡萄球菌(MRSA)占分离出的金黄色葡萄球菌菌株的21.1%。本文的分析表明,在波兰医院相对较新的环境中,有可能有效地实施统一的检测、鉴定和分析方法,在这些医院,现代医院流行病学工具自90年代中期才开始使用。

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引用本文的文献

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