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腹颈(经裂孔)食管癌切除术在食管癌治疗中的应用

Abdominocervical (transhiatal) oesophagectomy in the management of oesophageal carcinoma.

作者信息

Gotley D C, Beard J, Cooper M J, Britton D C, Williamson R C

机构信息

Department of Surgery, Bristol Royal Infirmary, UK.

出版信息

Br J Surg. 1990 Jul;77(7):815-9. doi: 10.1002/bjs.1800770732.

Abstract

Fifty-four patients have undergone abdominocervical oesophagectomy for oesophageal carcinoma as an alternative to a conventional transthoracic approach. Their median age was 69 years, with a range of 38-90 years, and 39 per cent of patients had chronic cardiorespiratory disease. Lymph node metastases were found in 80 per cent of patients and transmural tumour spread in 91 per cent. Median duration of operation was 2.2 h (range 1.75-6.0 h), and median transfusion requirement was 2.5 units (range 0-8 units). Respiratory complications were common (41 per cent) and caused all six postoperative deaths (11 per cent). Other complications were atrial fibrillation (26 per cent), transient recurrent laryngeal nerve palsy (11 per cent), cardiac failure (2 per cent), stroke (2 per cent), subphrenic abscess (2 per cent) and empyema (2 per cent). There were two anastomotic leaks (4 per cent), clinically manifest as temporary salivary fistulae. There have been 32 deaths from recurrent carcinoma, with a median duration of survival of 14 months (range 4-53 months). Fifteen patients are still alive, with a median survival of 16.5 months (range 3-49 months); the current 3-year survival rate is 10 per cent. All patients resumed normal swallowing after operation, but 11 of them developed anastomotic strictures requiring a median of three dilatations. Avoidance of formal thoracotomy by the abdominocervical approach may allow more rapid oesophagectomy without increasing the risk of postoperative death and gives a quality of palliation at least equivalent to that of conventional transthoracic oesophageal excision.

摘要

54例食管癌患者接受了经腹颈段食管切除术,作为传统经胸手术的替代方法。他们的中位年龄为69岁,范围在38 - 90岁之间,39%的患者患有慢性心肺疾病。80%的患者发现有淋巴结转移,91%有肿瘤穿透管壁扩散。中位手术时间为2.2小时(范围1.75 - 6.0小时),中位输血量为2.5单位(范围0 - 8单位)。呼吸并发症很常见(41%),且导致了所有6例术后死亡(11%)。其他并发症包括房颤(26%)、短暂性喉返神经麻痹(11%)、心力衰竭(2%)、中风(2%)、膈下脓肿(2%)和脓胸(2%)。有2例吻合口漏(4%),临床表现为暂时性唾液瘘。有32例患者死于复发癌,中位生存期为14个月(范围4 - 53个月)。15例患者仍然存活,中位生存期为16.5个月(范围3 - 49个月);目前的3年生存率为10%。所有患者术后吞咽功能均恢复正常,但其中11例出现吻合口狭窄,平均需要扩张3次。经腹颈段手术避免了正式开胸,可能使食管切除术更快进行,而不增加术后死亡风险,并且提供的姑息治疗质量至少与传统经胸食管切除术相当。

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