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在接受标准化白内障超声乳化手术的特定人群中,孔源性视网膜脱离的长期发病率及生存率

Longterm incidence of rhegmatogenous retinal detachment and survival in a defined population undergoing standardized phacoemulsification surgery.

作者信息

Boberg-Ans Gøril, Henning Vibeke, Villumsen Jørgen, la Cour Morten

机构信息

Eye Department, Copenhagen University Hospital, KAS-Herlev, Copenhagen, Denmark.

出版信息

Acta Ophthalmol Scand. 2006 Oct;84(5):613-8. doi: 10.1111/j.1600-0420.2006.00719.x.

Abstract

PURPOSE

To determine the longterm risk of pseudophakic retinal detachment (PRD) in a defined population undergoing standardized phacoemulsification surgery at a single centre.

DESIGN

We carried out a register-based, retrospective, consecutive, uncontrolled study. All 6352 eyes that underwent cataract surgery at our institution during the years 1996-1998 were included in the study. The main outcome measure was the incidence of surgery for PRD.

METHODS

Cataract-operated eyes were identified by a search in the local hospital registry. Eyes that subsequently underwent surgery for PRD were identified by a search in the Danish Patients Registry (LPR). Follow-up ended by 31 December 2003. Eyes in patients who died before that date were censored.

RESULTS

The 8-year cumulated incidence of PRD after phacoemulsification was 0.93 per eye (95% CI 0.65-1.33). This is 8.77 (95% CI 7.12-10.72) times higher than expected in eyes that do not undergo cataract surgery. The incidence rate for retinal detachment was significantly higher in pseudophakic eyes than in the background population for at least 6 years after surgery. Patient mortality was slightly increased for men, but no different for women from that of the background population.

CONCLUSION

For eyes undergoing phacoemulsification surgery, the cumulated incidence of PRD continues to increase for at least 8 years after surgery. Comparison of the cumulated incidence of PRD between different studies requires equal lengths of follow-up.

摘要

目的

确定在单一中心接受标准化超声乳化手术的特定人群中人工晶状体性视网膜脱离(PRD)的长期风险。

设计

我们开展了一项基于登记的回顾性、连续性、非对照研究。1996年至1998年期间在我们机构接受白内障手术的所有6352只眼被纳入研究。主要结局指标是PRD手术的发生率。

方法

通过在当地医院登记处搜索来识别接受白内障手术的眼睛。通过在丹麦患者登记处(LPR)搜索来识别随后接受PRD手术的眼睛。随访截至2003年12月31日。在此日期之前死亡患者的眼睛被截尾。

结果

超声乳化术后PRD的8年累积发生率为每只眼0.93(95%可信区间0.65 - 1.33)。这比未接受白内障手术的眼睛预期发生率高8.77(95%可信区间7.12 - 10.72)倍。术后至少6年,人工晶状体眼的视网膜脱离发生率显著高于一般人群。男性患者死亡率略有增加,但女性与一般人群无差异。

结论

对于接受超声乳化手术的眼睛,PRD的累积发生率在术后至少8年持续上升。不同研究间PRD累积发生率的比较需要相等的随访时长。

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