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屈光手术诊所白内障超声乳化术后视网膜脱离:16年可变随访的大样本系列分析

Retinal detachment after phacoemulsification in refractive surgery clinics: a large series analysis with variable follow-up during 16 years.

作者信息

Javaloy Jaime, Druchkiv Vasyl, Beltrán Jaime, Moya Jaime, Albarrán-Diego César, Montalbán Raúl, Muñoz Gonzalo

机构信息

Department of Refractive Surgery, Clínica Baviera Alicante, Alicante, Spain.

Department of Research and Development, Clínica Baviera Valencia, Valencia, Spain.

出版信息

Graefes Arch Clin Exp Ophthalmol. 2021 Jun;259(6):1555-1567. doi: 10.1007/s00417-021-05160-w. Epub 2021 Mar 31.

Abstract

PURPOSE

To determine the long-term incidence of pseudophakic retinal detachment (PRD) after phacoemulsification and the weight of the main risk factors in the appearance of such complication in a large sample. To implement a customized formula and a software calculation program able to quantify the risk of suffering PRD applicable to all lens extraction patients.

METHODS

Retrospective cumulative risk analysis conducted on 178,515 eyes operated under similar conditions in a group of refractive surgery clinics (Clínica Baviera SL) located in a relatively limited geographical area (Spain). A survival analysis was performed and the data were modelled using the Weibull regression to determine the risk over a period of 16 years and to estimate the association of different risk factors: sex, age, axial length (AXL) of the eye, intraoperative posterior capsule rents (PCR), and YAG laser capsulotomies. The resulting estimates were translated into a predictive equation for hazard rates and survival probabilities. Later, an application was developed to make prediction available for the clinical community in order to estimate the potential risk of any hypothetical case before lens surgery.

RESULTS

Globally, 1521 (0.85%) cases of PRD were diagnosed during the period. The risk for PRD was significantly greater in males (5.48 [2.94-10.2]; p < 0.001), in long eyes (1.24 [1.21-1.26]; p < 0.001), and also after posterior capsule rents (13.97 [11.61-16.82]; p < 0.001). Posterior capsule rupture increased the risk of PRD up to fourteen times.

CONCLUSIONS

From weaker to stronger impact, age, axial length, sex, and intraoperative posterior capsule rent were significant risk factors for the appearance of PRD after lens extraction.

摘要

目的

确定白内障超声乳化术后人工晶状体眼视网膜脱离(PRD)的长期发生率,以及在大样本中出现此类并发症的主要危险因素的权重。实施一个定制公式和软件计算程序,能够量化适用于所有晶状体摘除患者发生PRD的风险。

方法

对位于相对有限地理区域(西班牙)的一组屈光手术诊所(Clínica Baviera SL)中178,515只在相似条件下接受手术的眼睛进行回顾性累积风险分析。进行生存分析,并使用威布尔回归对数据进行建模,以确定16年内的风险,并估计不同危险因素的关联:性别、年龄、眼轴长度(AXL)、术中后囊膜破裂(PCR)和YAG激光后囊切开术。将所得估计值转化为危险率和生存概率的预测方程。随后,开发了一个应用程序,以便临床界能够进行预测,从而在晶状体手术前估计任何假设病例的潜在风险。

结果

总体而言,在此期间诊断出1521例(0.85%)PRD病例。男性发生PRD的风险显著更高(5.48 [2.94 - 10.2];p < 0.001),眼轴长的眼睛(1.24 [1.21 - 1.26];p < 0.001),以及后囊膜破裂后(13.97 [11.61 - 16.82];p < 0.001)。后囊膜破裂使PRD的风险增加高达14倍。

结论

从影响较弱到较强,年龄、眼轴长度、性别和术中后囊膜破裂是晶状体摘除后发生PRD的重要危险因素。

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