Lovelace Christopher T, Elmore Wade R, Filion Diane L
Department of Psychology, University of Missouri-Kansas City, Kansas City, Missouri 64110, USA.
Psychophysiology. 2006 Sep;43(5):511-5. doi: 10.1111/j.1469-8986.2006.00449.x.
The "gold standard" measure of the human startle eyeblink response is the ocular electromyogram (EMG). However, EMG measurement is not always feasible, as with special populations or during functional neuroimaging. We evaluated an alternative, nonelectrical, noncontact measure that uses infrared (IR) light reflected from the eye. By simultaneously recording IR and EMG during an acoustic prepulse inhibition of startle paradigm, we were able to directly compare the two measures and evaluate the relative reliability and validity of the IR measure as an index of startle response modulation. Although fewer responses were detected using IR than EMG, both measures were equally sensitive to prepulse modulation of response amplitude, latency, and probability. We conclude that when the goal is simply to assess the effects of a prepulse on the startle response, IR reflectance is an adequate alternative to EMG.
人类惊跳眨眼反应的“金标准”测量方法是眼肌电图（EMG）。然而，EMG测量并不总是可行的，比如对于特殊人群或在功能神经成像过程中。我们评估了一种替代性的、非电的、非接触式测量方法，该方法利用从眼睛反射的红外（IR）光。通过在惊吓前脉冲抑制范式期间同时记录IR和EMG，我们能够直接比较这两种测量方法，并评估IR测量作为惊吓反应调节指标的相对可靠性和有效性。尽管使用IR检测到的反应比EMG少，但两种测量方法对反应幅度、潜伏期和概率的前脉冲调制同样敏感。我们得出结论，当目标仅仅是评估前脉冲对惊吓反应的影响时，IR反射率是EMG的一种合适替代方法。
