Nedialkov Iu A, Spitsyn S V, Drobyshevskaia E I, Gosteva V V, Klitsunova N V, Smirnova N S, Tarasevich I V, Nesterenko V G
Zh Mikrobiol Epidemiol Immunobiol. 1990 May(5):94-7.
R. prowazekii antigens have been tested with the use of monoclonal antibodies (McAb) to different epitopes of the microorganism. As revealed in these tests, McAb B4/4 and A-3/D, active against species-specific thermolabile antigen, interact with protein having a molecular weight of 90-120 KD. McAb C5/2, active against thermostable group antigen common with that of Rickettsia typhi, interact with LPS-like antigen having a molecular weight of 30 KD. Ultrastructural immunochemical studies have revealed that both R. prowazekii antigens are located on surface structures of rickettsiae, such as the microcapsule and cell wall.
